Synthesis, structure, and antimicrobial activity of methyl (4-alkanoyl-1,5-diaryl-2-hydroxy-3-oxo-2,3-dihydro-1H-pyrrol-2-yl)acetates

被引：0
|
作者：
P. P. Mukovoz
A. V. Gorbunova
P. A. Slepukhin
O. S. El’tsov
I. N. Ganebnykh
A. N. Sizentsov
I. V. Korobova
机构：
[1] Moscow Institute of Technology,Orenburg Branch
[2] Orenburg State University,Postovskii Institute of Organic Synthesis, Ural Branch
[3] Russian Academy of Sciences,undefined
[4] Yeltsin Ural Federal University,undefined
来源：
Russian Journal of General Chemistry | 2017年 / 87卷
关键词：
3,4-dihydroxy-6-oxo-2,4-alkadienoic acid esters; (4-alkanoyl-1,5-diaryl-2-hydroxy-3-oxo-2,3-dihydro-1; -pyrrol-2-yl)acetic acid esters; 1,3,4,6-tetracarbonyl compounds;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Reactions of methyl 3,4,6-trioxoalkanoates (3,4-dihydroxy-6-oxo-2,4-alkadienoates) with mixtures of aromatic aldehydes and arylamines or with the corresponding N-(arylmethylidene)anilines afforded methyl (4-alkanoyl-1,5-diaryl-2-hydroxy-3-oxo-2,3-dihydro-1H-pyrrol-2-yl)acetates. The product structure was discussed on the basis of their IR, 1H NMR, and mass spectra and X-ray diffraction data, and their antimicrobial activity against Staphylococcus aureus P-209 and Escherichia coli M17 was evaluated.
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页码：1695 / 1701
页数：6
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