Ultrasensitive Detection of Cu2+ Using a Microcantilever Sensor Modified with L-Cysteine Self-Assembled Monolayer

被引：0
作者：
Xiaohe Xu
Na Zhang
Gilbert M. Brown
Thomas G. Thundat
Hai-Feng Ji
机构：
[1] Drexel University,Department of Chemistry
[2] Oak Ridge National Laboratory,Chemical Sciences Division
[3] University of Alberta,Department of Chemical and Materials Engineering
来源：
Applied Biochemistry and Biotechnology | 2017年 / 183卷
关键词：
Microcantilevers; Cu; detection; Adsorption-induced stress; Self-assembled monolayers (SAM); Chemically modified surfaces; And L-cysteine;
D O I：
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中图分类号：
学科分类号：
摘要：
A microcantilever was modified with a self-assembled monolayer (SAM) of L-cysteine for the sensitively and selectively response to Cu(II) ions in aqueous solution. The microcantilever undergoes bending due to sorption of Cu(II) ions. The interaction of Cu(II) ions with the L-cysteine on the cantilever is diffusion controlled and does not follow a simple Langmuir adsorption model. A concentration of 10−10 M Cu(II) was detected in a fluid cell using this technology. Other cations, such as Ni2+, Zn2+, Pb2+, Cd2+, Ca2+, K+, and Na+, did not respond with a significant deflection, indicating that this L-cysteine-modified cantilever responded selectively and sensitively to Cu(II).
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页码：555 / 565
页数：10
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