The Down-Regulation of Notch1 Inhibits the Invasion and Migration of Hepatocellular Carcinoma Cells by Inactivating the Cyclooxygenase-2/Snail/E-cadherin Pathway In Vitro

被引:0
作者
Liang Zhou
De-sheng Wang
Qing-jun Li
Wei Sun
Yong Zhang
Ke-feng Dou
机构
[1] The Fourth Military Medical University,Department of Hepatobiliary Surgery, Xijing Hospital
来源
Digestive Diseases and Sciences | 2013年 / 58卷
关键词
Notch1 signaling pathway; E-cadherin; Snail; Cyclooxygenase-2; Invasion; Migration;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1016 / 1025
页数:9
相关论文
共 50 条
  • [41] Knockdown of linc-OIP5 inhibits proliferation and migration of glioma cells through down-regulation of YAP-NOTCH signaling pathway
    Hu, Guo-wen
    Wu, Lei
    Kuang, Wei
    Chen, Yong
    Zhu, Xin-gen
    Guo, Hua
    Lang, Hai-li
    GENE, 2017, 610 : 24 - 31
  • [42] E-cadherin loss in RMG-1 cells inhibits cell migration and its regulation by Rho GTPases
    Haraguchi, Misako
    Fukushige, Tomoko
    Kanekura, Takuro
    Ozawa, Masayuki
    BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2019, 18
  • [43] Down-regulation expression of TGFB2-AS1 inhibits the proliferation, migration, invasion and induces apoptosis in HepG2 cells
    Wenrong Liu
    Ruiping Huai
    Yin Zhang
    Shuquan Rao
    Lili xiong
    Ruofan Ding
    Canquan Mao
    Wenqing Zhao
    Tao Hao
    Qingqing Huang
    Zhiyun Guo
    Genes & Genomics, 2019, 41 : 951 - 959
  • [44] P2Y2 receptor promotes the migration and invasion of breast cancer cells via EMT-related genes Snail and E-cadherin
    Qiu, Ying
    Liu, Yan
    Li, Wei-Hua
    Zhang, Hong-Quan
    Tian, Xin-Xia
    Fang, Wei-Gang
    ONCOLOGY REPORTS, 2018, 39 (01) : 138 - 150
  • [45] The Down-Regulation of SUZ12 Accelerates the Migration and Invasion of Liver Cancer Cells via Activating ERK1/2 Pathway
    Xue, Cailin
    Wang, Kunyuan
    Jiang, Xiaofeng
    Gu, Chengxin
    Yu, Ganxiang
    Zhong, Yun
    Liu, Shiming
    Nie, Yuqiang
    Zhou, Yongjian
    Yang, Hui
    JOURNAL OF CANCER, 2019, 10 (06): : 1375 - 1384
  • [46] Hypoxia-inducible factor 1 alpha mediates epidermal growth factor-induced down-regulation of E-cadherin expression and cell invasion in human ovarian cancer cells
    Cheng, Jung-Chien
    Klausen, Christian
    Leung, Peter C. K.
    CANCER LETTERS, 2013, 329 (02) : 197 - 206
  • [47] Protein kinase D1 induced epithelial-mesenchymal transition and invasion in salivary adenoid cystic carcinoma via E-cadherin/Snail regulation
    Du, Yue
    Lv, Die
    Cui, Bomiao
    Li, Xiaoying
    Chen, Hongli
    Kang, Yingzhu
    Chen, Qianming
    Feng, Yun
    Zhang, Ping
    Chen, Jiao
    Zhou, Xuedong
    ORAL DISEASES, 2022, 28 (06) : 1539 - 1554
  • [48] HES1-mediated down-regulation of miR-138 sustains NOTCH1 activation and promotes proliferation and invasion in renal cell carcinoma
    Shuangjie Liu
    Lei Dou
    Miao Miao
    Xiaojun Man
    Baojun Wei
    Zhaowei Jiang
    Yongze Ouyang
    Toshinori Ozaki
    Meng Yu
    Yuyan Zhu
    Journal of Experimental & Clinical Cancer Research, 42
  • [49] LncRNA FUNDC2P4 down-regulation promotes epithelial-mesenchymal transition by reducing E-cadherin expression in residual hepatocellular carcinoma after insufficient radiofrequency ablation
    Zeng, Jiangzheng
    Cai, Xinrui
    Hao, Xinbao
    Huang, Fen
    He, Zhihui
    Sun, Huamao
    Lu, Yanda
    Lei, Junhua
    Zeng, Wangyuan
    Liu, Yu
    Luo, Rongcheng
    INTERNATIONAL JOURNAL OF HYPERTHERMIA, 2018, 34 (06) : 802 - 811
  • [50] HES1-mediated down-regulation of miR-138 sustains NOTCH1 activation and promotes proliferation and invasion in renal cell carcinoma
    Liu, Shuangjie
    Dou, Lei
    Miao, Miao
    Man, Xiaojun
    Wei, Baojun
    Jiang, Zhaowei
    Ouyang, Yongze
    Ozaki, Toshinori
    Yu, Meng
    Zhu, Yuyan
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2023, 42 (01)