Differences in functional magnetic resonance imaging of sensorimotor cortex during static and dynamic finger flexion

被引：0

作者：

G. W. Thickbroom

B. A. Phillips

I. Morris

M. L. Byrnes

P. Sacco

F. L. Mastaglia

机构：

[1] Australian Neuromuscular Research Institute,

[2] Queen Elizabeth II Medical Centre,undefined

[3] Nedlands,undefined

[4] WA6009,undefined

[5] Australia e-mail: gthickbr@cyllene.uwa.edu.au Tel.: +61-8-9346-1598,undefined

[6] Fax: +61-8-9346-3487,undefined

[7] MRI Unit,undefined

[8] Department of Radiology,undefined

[9] Sir Charles Gairdner Hospital,undefined

[10] Western Australia,undefined

[11] Australia,undefined

[12] Department of Medicine,undefined

[13] University of Western Australia,undefined

[14] Western Australia,undefined

[15] Australia,undefined

[16] Department of Neurology and Clinical Neurophysiology,undefined

[17] Sir Charles Gairdner Hospital,undefined

[18] Western Australia,undefined

[19] Australia,undefined

[20] School of Biomedical and Sports Science,undefined

[21] Edith Cowan University,undefined

[22] Western Australia,undefined

[23] Australia,undefined

来源：

Experimental Brain Research | 1999年 / 126卷

关键词：

Key words fMRI; Static; Dynamic; Sensorimotor cortex;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Functional magnetic resonance imaging (fMRI) studies of the human motor system have commonly used movement paradigms which contain a dynamic component; however, the relationship between the fMRI signal for motor tasks with and without a dynamic component is not known. We have investigated the relationship between the fMRI signal during a static finger flexion task and during dynamic finger flexion at 1–3 Hz, each at two levels of force (5% and 10% of maximum voluntary contraction). A small fMRI response could be recorded from only a few subjects during the static tasks. In contrast, a substantial fMRI response occurred during dynamic tasks in all subjects at both levels of force. The fMRI response was not significantly correlated with force or movement rate during the dynamic tasks. It is concluded that the factors responsible for generating an fMRI response are fundamentally different during steady contractions compared to those involving a dynamic component, and that the fMRI signal may be more sensitive to changes in the pattern of neural activation rather than the ongoing firing rate or extent of activation.

引用

页码：431 / 438

页数：7