Mutations in the MTHFR gene are not associated with Methotrexate intolerance in patients with juvenile idiopathic arthritis

[1] Hashkes PJ(2005)Medical treatment of juvenile idiopathic arthritis JAMA 294 1671-84

[2] Laxer RM(2005)Evidence-based use of methotrexate in children with rheumatic diseases: a consensus statement of the Working Groups Pediatric Rheumatology Germany (AGKJR) and Pediatric Rheumatology Austria Rheumatol Int 25 169-78

[3] Niehues T(2002)Advanced therapy for juvenile arthritis Best Pract Res Clin Rheumatol 16 361-78

[4] Horneff G(2011)Anticipatory nausea and vomiting Support Care Cancer 19 1533-8

[5] Michels H(2012)Methylene tetrahydrofolate reductase gene polymorphisms and their association with methotrexate toxicity: a meta-analysis Pharmacogenet Genomics 22 117-33

[6] Hock MS(2013)Prevalence of methotrexate intolerance in rheumatoid arthritis and psoriatic arthritis Arthritis Res Ther 15 R217-7

[7] Schuchmann L(2002)Implications on human fertility of the 677C- > T and 1298A- > C polymorphisms of the MTHFR gene: consequences of a possible genetic selection Mol Hum Reprod 8 952-60

[8] Murray KJ(1998)Worldwide distribution of a common methylenetetrahydrofolate reductase mutation Am J Hum Genet 62 1258-51

[9] Lovell DJ(1998)A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet 62 1044-7

[10] Roscoe JA(2014)Methotrexate-induced nausea and vomiting in adolescent and young adult patients Clin Rheumatol 33 403-7

[1] Hashkes PJ(2005)Medical treatment of juvenile idiopathic arthritis JAMA 294 1671-84

[2] Laxer RM(2005)Evidence-based use of methotrexate in children with rheumatic diseases: a consensus statement of the Working Groups Pediatric Rheumatology Germany (AGKJR) and Pediatric Rheumatology Austria Rheumatol Int 25 169-78

[3] Niehues T(2002)Advanced therapy for juvenile arthritis Best Pract Res Clin Rheumatol 16 361-78

[4] Horneff G(2011)Anticipatory nausea and vomiting Support Care Cancer 19 1533-8

[5] Michels H(2012)Methylene tetrahydrofolate reductase gene polymorphisms and their association with methotrexate toxicity: a meta-analysis Pharmacogenet Genomics 22 117-33

[6] Hock MS(2013)Prevalence of methotrexate intolerance in rheumatoid arthritis and psoriatic arthritis Arthritis Res Ther 15 R217-7

[7] Schuchmann L(2002)Implications on human fertility of the 677C- > T and 1298A- > C polymorphisms of the MTHFR gene: consequences of a possible genetic selection Mol Hum Reprod 8 952-60

[8] Murray KJ(1998)Worldwide distribution of a common methylenetetrahydrofolate reductase mutation Am J Hum Genet 62 1258-51

[9] Lovell DJ(1998)A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet 62 1044-7

[10] Roscoe JA(2014)Methotrexate-induced nausea and vomiting in adolescent and young adult patients Clin Rheumatol 33 403-7