Design, synthesis and antitumor activity evaluation of pyrimidine derivatives containing 4-hydroxypiperidine group

[1] Ye T(2020)Design, synthesis and biological evaluation of novel 2,4-bismorpholinothieno[3,2-d]pyrimidine and 2-morpholinothieno[3,2-d]pyrimidinone derivatives as potent antitumor agents Bioorg Chem 99 103796-64

[2] Han Y(2019)Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers Bioorg Chem 88 102944-9

[3] Wang R(2022)Complete surgical excision is necessary following vacuum-assisted biopsy for breast cancer Curr Oncol 29 9357-8

[4] Yan P(2022)Concordance between core needle biopsy and surgical excision for breast cancer tumor grade and biomarkers Breast Cancer Res Treat 193 151-92

[5] Chen S(2022)Survival after induction chemotherapy and chemoradiation versus chemoradiation and adjuvant chemotherapy for locally advanced rectal cancer Oncologist. 27 380-e15

[6] Hou Y(2022)Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8 Sci Adv 8 eabh4050-68

[7] Elmetwally SA(2022)Multicenter, randomized, phase III trial of short-term radiotherapy plus chemotherapy versus long-term chemoradiotherapy in Locally Advanced Rectal Cancer (STELLAR) J Clin Oncol 40 1681-44

[8] Saied KF(2022)Stereotactic body radiotherapy plus pembrolizumab and trametinib versus stereotactic body radiotherapy plus gemcitabine for locally recurrent pancreatic cancer after surgical resection: an open-label, randomised, controlled, phase 2 trial Lancet Oncol 23 e105-70

[9] Eissa IH(2022)Design, synthesis and anti-tumor activity evaluation of 4,6,7-substitute quinazoline derivatives Med Chem Res 31 1351-8

[10] Elkaeed EB(2021)Design, synthesis, and antitumor activity evaluation of steroidal oximes Bioorg Med Chem 46 116360.-62

[1] Ye T(2020)Design, synthesis and biological evaluation of novel 2,4-bismorpholinothieno[3,2-d]pyrimidine and 2-morpholinothieno[3,2-d]pyrimidinone derivatives as potent antitumor agents Bioorg Chem 99 103796-64

[2] Han Y(2019)Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers Bioorg Chem 88 102944-9

[3] Wang R(2022)Complete surgical excision is necessary following vacuum-assisted biopsy for breast cancer Curr Oncol 29 9357-8

[4] Yan P(2022)Concordance between core needle biopsy and surgical excision for breast cancer tumor grade and biomarkers Breast Cancer Res Treat 193 151-92

[5] Chen S(2022)Survival after induction chemotherapy and chemoradiation versus chemoradiation and adjuvant chemotherapy for locally advanced rectal cancer Oncologist. 27 380-e15

[6] Hou Y(2022)Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8 Sci Adv 8 eabh4050-68

[7] Elmetwally SA(2022)Multicenter, randomized, phase III trial of short-term radiotherapy plus chemotherapy versus long-term chemoradiotherapy in Locally Advanced Rectal Cancer (STELLAR) J Clin Oncol 40 1681-44

[8] Saied KF(2022)Stereotactic body radiotherapy plus pembrolizumab and trametinib versus stereotactic body radiotherapy plus gemcitabine for locally recurrent pancreatic cancer after surgical resection: an open-label, randomised, controlled, phase 2 trial Lancet Oncol 23 e105-70

[9] Eissa IH(2022)Design, synthesis and anti-tumor activity evaluation of 4,6,7-substitute quinazoline derivatives Med Chem Res 31 1351-8

[10] Elkaeed EB(2021)Design, synthesis, and antitumor activity evaluation of steroidal oximes Bioorg Med Chem 46 116360.-62