The Synthesis of Cholesterol-Containing Cationic Amphiphils with Heterocyclic Bases

被引：0
|
作者：
T. V. Konstantinova
V. N. Klykov
G. A. Serebrennikova
机构：
[1] Lomonosov State Academy of Fine Chemical Technology,
来源：
Russian Journal of Bioorganic Chemistry | 2001年 / 27卷
关键词：
cholesterol cationic derivatives; transfection;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A number of cationic derivatives of cholesterol containing polar residues of N-methylimidazole, pyridine, N-methylmorpholine, and 4-N,N-dimethyaminopyridine were synthesized by the interaction of the corresponding heterocyclic bases with cholesterol 5-bromopentanoate followed by the treatment with methyl iodide in the case of tertiary amines. In addition, N-(4-cholesteryloxycarbonylbutyl)piperazine was obtained for the preparation of pH-sensitive liposomes.
引用
收藏
页码：404 / 407
页数：3
相关论文
共 50 条
  • [21] THERMODYNAMIC INSTABILITY OF CHOLESTEROL-CONTAINING VESICLES
    LOMAKIN, AV
    NOSKIN, VA
    ROZENBERG, OA
    SHMELEV, GE
    MOLECULAR BIOLOGY, 1983, 17 (02) : 197 - 203
  • [22] Cholesterol lipids and cholesterol-containing lipid rafts in bacteria
    Huang, Zhen
    London, Erwin
    CHEMISTRY AND PHYSICS OF LIPIDS, 2016, 199 : 11 - 16
  • [23] MESOMORPHOUS STATE OF CHOLESTEROL-CONTAINING OLIGOESTERURETHANES
    TSUKRUK, VV
    SHILOV, VV
    SHEVCHENKO, VV
    SHRUBOVICH, VA
    LIPATOV, YS
    DOPOVIDI AKADEMII NAUK UKRAINSKOI RSR SERIYA B-GEOLOGICHNI KHIMICHNI TA BIOLOGICHNI NAUKI, 1982, (09): : 49 - 51
  • [24] CHOLESTEROL-CONTAINING GRANULOMA OF THE ORBITAL WALL
    NICHOLLS, JVV
    AMERICAN JOURNAL OF OPHTHALMOLOGY, 1956, 41 (02) : 234 - 247
  • [25] Synthesis and Degradation of Schiff Bases Containing Heterocyclic Pharmacophore
    Ledeti, Ionut
    Alexa, Anda
    Bercean, Vasile
    Vlase, Gabriela
    Vlase, Titus
    Suta, Lenuta-Maria
    Fulias, Adriana
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2015, 16 (01): : 1711 - 1727
  • [26] LIQUID-CRYSTAL CHOLESTEROL-CONTAINING POLYMERS
    SHIBAEV, VP
    FREIDZON, YS
    PLATE, NA
    DOKLADY AKADEMII NAUK SSSR, 1976, 227 (06): : 1412 - 1415
  • [27] STUDY OF INTRAMOLECULAR INTERACTIONS IN CHOLESTEROL-CONTAINING POLYMERS
    ANUFRIEVA, EV
    PAUTOV, VD
    FREIDZON, YS
    SHIBAEV, VP
    VYSOKOMOLEKULYARNYE SOEDINENIYA SERIYA A, 1977, 19 (04): : 755 - 758
  • [28] Immune Implications of Cholesterol-Containing Lipid Nanoparticles
    Back, Patricia Ines
    Yu, Minzhi
    Modaresahmadi, Shadan
    Hajimirzaei, Sahelosadat
    Zhang, Qisheng
    Islam, Md Rakibul
    Schwendeman, Anna A.
    La-Beck, Ninh M.
    ACS NANO, 2024, 18 (42) : 28480 - 28501
  • [29] ANEMIA OF RABBITS FED A CHOLESTEROL-CONTAINING DIET
    PINTER, GG
    BAILEY, RE
    AMERICAN JOURNAL OF PHYSIOLOGY, 1961, 200 (02): : 292 - &
  • [30] FEATURES OF LAYER ORDERING OF CHOLESTEROL-CONTAINING POLYMERS
    FREIDZON, YS
    TROPSHA, YG
    TSUKRUK, VV
    SHILOV, VV
    SHIBAEV, VP
    LIPATOV, YS
    VYSOKOMOLEKULYARNYE SOEDINENIYA SERIYA A, 1987, 29 (07): : 1371 - 1376
12345