Targeting PPARα in the rat valproic acid model of autism: focus on social motivational impairment and sex-related differences

被引:0
作者
Simona Scheggi
Francesca Guzzi
Giulia Braccagni
Maria Graziella De Montis
Marco Parenti
Carla Gambarana
机构
[1] University of Siena,Department Molecular and Developmental Medicine
[2] University of Milano-Bicocca,Department Medicine and Surgery
来源
Molecular Autism | / 11卷
关键词
Autism spectrum disorder; Reward; Dopamine; Valproic acid; Animal models;
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[1]  
Leekam S(2016)Social cognitive impairment and autism: what are we trying to explain? Philos Trans. R. Soc. B Biol. Sci. 371 20150082-239
[2]  
Chevallier C(2012)The social motivation theory of autism Trends Cogn. Sci. 16 231-259
[3]  
Kohls G(2012)Social ‘wanting’ dysfunction in autism: neurobiological underpinnings and treatment implications J. Neurodev. Disord. 4 10-536
[4]  
Troiani V(2016)PPARα modulation of mesolimbic dopamine transmission rescues depression-related behaviors Neuropharmacology 110 251-89
[5]  
Brodkin ES(2015)Peroxisome proliferator-activated receptor alpha plays a crucial role in behavioral repetition and cognitive flexibility in mice Mol. Metab. 4 528-1844
[6]  
Schultz RT(2005)Behavioral Alterations in Rats Prenatally Exposed to Valproic Acid: Animal Model of Autism Neuropsychopharmacology 30 80-257
[7]  
Kohls G(2017)Social motivation and implicit theory of mind in children with autism spectrum disorder Autism Res. 10 1834-298
[8]  
Chevallier C(2007)Emotional and cognitive changes during adolescence Curr. Opin. Neurobiol. 17 251-202
[9]  
Troiani V(2019)Prenatal valproate in rodents as a tool to understand the neural underpinnings of social dysfunctions in autism spectrum disorder Neuropharmacology 159 107477-167
[10]  
Schultz RT(2013)Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice J. Vis. Exp 82 50978-1792