The role of fatty acids in insulin resistance

被引：0
|
作者：
Barry Sears
Mary Perry
机构：
[1] Inflammation Research Foundation,
来源：
Lipids in Health and Disease | / 14卷
关键词：
Insulin resistance; Inflammation; Fatty acids; Palmitic acid; Omega-3 fatty acids; Hypothalamus; Adipose tissue; Liver; Muscle; Endotoxemia;
D O I：
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摘要：
Insulin resistance is a multi-faceted disruption of the communication between insulin and the interior of a target cell. The underlying cause of insulin resistance appears to be inflammation that can either be increased or decreased by the fatty acid composition of the diet. However, the molecular basis for insulin resistance can be quite different in various organs. This review deals with various types of inflammatory inputs mediated by fatty acids, which affect the extent of insulin resistance in various organs.
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