Two-year long safety and efficacy of deferasirox film-coated tablets in patients with thalassemia or lower/intermediate risk MDS: phase 3 results from a subset of patients previously treated with deferasirox in the ECLIPSE study

被引:0
作者
Immacolata Tartaglione
Raffaella Origa
Antonis Kattamis
Michael Pfeilstöcker
Sibel Gunes
Susanne Crowe
Niamh Fagan
Beatrice Vincenzi
Giovan Battista Ruffo
机构
[1] University of Campania Luigi Vanvitelli,Department of Woman, Child and of General and Specialist Surgery
[2] Ospedale Pediatrico Microcitemico “A.Cao,Division of Pediatric Hematology
[3] ” A.O. “G.Brotzu”,Oncology, First Department of Pediatrics
[4] National and Kapodistrian University of Athens,Third Medical Department
[5] Hanusch Hospital,undefined
[6] Novartis Farma SPA,undefined
[7] Novartis Ireland Limited,undefined
[8] U.O.C. Ematologia e Talassemia,undefined
[9] A.O. Civico-Di Cristina-Benfratelli,undefined
来源
Experimental Hematology & Oncology | / 9卷
关键词
Deferasirox; Chelation; Film-coated tablet; Iron overload; Long-term; Safety; Transfusion-dependent thalassemia; Myelodysplastic syndrome;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 65 条
[1]  
Cheng WY(2018)Adherence to iron chelation therapy in patients who switched from deferasirox dispersible tablets to deferasirox film-coated tablets Curr Med Res Opin 34 1959-1966
[2]  
Said Q(2018)Optimising management of deferasirox therapy for patients with transfusion-dependent thalassaemia and lower-risk myelodysplastic syndromes Eur J Haematol 101 272-282
[3]  
Hao Y(2011)Challenges of adherence and persistence with iron chelation therapy Int J Hematol 94 453-460
[4]  
Xiao Y(2010)Beta-thalassemia Orphanet J Rare Dis. 5 11-403
[5]  
Vekeman F(2013)Impact of heart magnetic resonance imaging on chelation choices, compliance with treatment and risk of heart disease in patients with thalassaemia major Br J Haematol 163 400-1929
[6]  
Bobbili P(2008)Impact of compliance, ferritin and LIC on long-term trends in myocardial T2* with deferasirox Blood 112 116-144
[7]  
Kattamis A(2007)Consequences and costs of noncompliance with iron chelation therapy in patients with transfusion-dependent thalassemia: a literature review Transfusion. 47 1919-181
[8]  
Aydinok Y(2019)Strategies for managing transfusional iron overload: conventional treatments and novel strategies Curr Opin Hematol 26 139-952
[9]  
Taher A(2012)Persistence and compliance of deferoxamine versus deferasirox in Medicaid patients with sickle-cell disease J Clin Pharm Ther 37 173-428
[10]  
Porter JB(2018)The effect of iron chelation therapy on overall survival in sickle cell disease and β-thalassemia: a systematic review Am J Hematol 93 943-514