Submucosal Endoscopic Resection of Rectal GEP-NETs Is Curative—a Case Series Analysis

Rectal neuroendocrine tumors are usually small-sized lesions detected incidentally by colonoscopy and their survival rate is high. In its treatment, endoscopic mucosal resection and endoscopic submucosal dissection are frequently used. In this study, we aimed to retrospectively evaluate the patients who underwent endoscopic resection due to rectal neuroendocrine tumor. Seven patients who underwent endoscopic resection due to rectal neuroendocrine tumor in gastroenterology surgery endoscopy unit between 2015 and 2019 were included in the study. The cases were evaluated in terms of age, gender, tumor size, histopathology result, complete excision, en bloc excision, performed procedure, complication, additional procedure, referral to surgery, number of follow-up, follow-up time, and recurrence. The mean lesion size was 1.14 (0.8–1.5) cm. Histopathology results of all cases were evaluated as grade 1 neuroendocrine tumor. Complete excision and en bloc excision were performed in all cases. No complications were observed in the cases. No recurrence was observed in the cases. Endoscopic submucosal dissection and endoscopic mucosal resection can be safely used with high complete excision rate and low possibility of complications if the lesion is below 1.5 cm, and there is no muscle layer invasion in rectal neuroendocrine tumors.