Cardiohepatic syndrome: Liver injury in decompensated heart failure

被引：60

作者：

Laribi S. ^{[1
,2
]}

Mebazaa A. ^{[2
,3
,4
,5
]}

机构：

[1] Emergency Department, APHP, Groupe Hospitalier Saint Louis-Lariboisière

[2] BIOmarkers in CArdioNeuroVAScular Diseases, INSERM

[3] Univ. Paris Diderot, Sorbonne Paris Cité

[4] Department of Anesthesiology and Critical Care, APHP, Groupe Hospitalier Saint Louis-Lariboisière

[5] Department of Anesthesiology and Critical Care, Hôpital Lariboisière, 2 Rue Ambroise Paré

来源：

Current Heart Failure Reports | 2014年 / 11卷 / 3期

关键词：

Acute heart failure; Cardiohepatic syndrome; Congestion; Liver function tests;

D O I：

10.1007/s11897-014-0206-8

中图分类号：

学科分类号：

摘要：

Heart failure (HF) is a major healthcare concern. Acute HF carries a high mortality and a high rehospitalisation rate. HF has a variety of detrimental effects on other organs. In recent years, the interactions between heart failure and the kidney have been the subject of significant investigations; this interaction, defined as "cardiorenal syndrome", is relatively well characterized. We describe here another interaction between the heart and the liver, the "cardiohepatic syndrome", in acute HF patients. Recent publications have shown that liver function test (LFT) abnormalities were associated with AHF severity. Clinical signs of systemic congestion were found to be associated with cholestasis, when signs of hypoperfusion were associated with liver cytolysis. Defining the LFT profile in AHF may play an important role in the future management of AHF patients. © 2014 Springer Science+Business Media.

引用

页码：236 / 240

页数：4

共 32 条

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