A refined Monte Carlo code for low-energy electron emission from gold material irradiated with sub-keV electrons

被引:0
作者
Li-Heng Zhou
Shui-Yan Cao
Tao Sun
Yun-Long Wang
Jun Ma
机构
[1] Nanjing University of Aeronautics and Astronautics,Department of Materials Science and Technology
[2] Nanjing University of Aeronautics and Astronautics,College of Physics, MIIT Key Laboratory of Aerospace Information Materials and Physics
[3] University of Science and Technology of China,School of Nuclear Science and Technology
来源
Nuclear Science and Techniques | 2023年 / 34卷
关键词
Monte Carlo code; Secondary electron emission; Low-energy electrons;
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摘要
Considering the significance of low-energy electrons (LEEs; 0–20 eV) in radiobiology, the sensitization potential of gold nanoparticles (AuNPs) as high-flux LEE emitters when irradiated with sub-keV electrons has been suggested. In this study, a track-structure Monte Carlo simulation code using the dielectric theory was developed to simulate the transport of electrons below 50 keV in gold. In this code, modifications, particularly for elastic scattering, are implemented for a more precise description of the LEE emission in secondary electron emission. This code was validated using the secondary electron yield and backscattering coefficient. To ensure dosimetry accuracy, we further verified the code for energy deposition calculations using the Monte Carlo toolkit, Geant4. The development of this code provides a basis for future studies regarding the role of AuNPs in targeted radionuclide radiotherapy.
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  • [1] Kereiakes JG(1992)Auger electron dosimetry: report of AAPM Nuclear Medicine Committee Task Group No. 6 Med. Phys. 19 1359-366
  • [2] Rao DV(2008)Therapeutic radionuclides: biophysical and radiobiologic principles Semin. Nucl. Med. 38 358-1992
  • [3] Kassis AI(2021)Microdosimetric investigation of the radiation quality of low-medium energy electrons using Geant4-DNA Appl. Radiat. Isot. 172 109654-1456
  • [4] Kyriakou I(1996)Targeted radiotherapy using Auger electron emitters Phys. Med. Biol. 41 1973-390
  • [5] Tremi I(2002)Ionization and excitation yields in liquid water due to the primary irradiation: Relationship of radiolysis with far UV-photolysisPresented at the Symposium on Recent Trends in Photochemical Sciences, Trivandrum, January 8–10, 2000 Phys. Chem. Chem. Phys. 4 1451-1660
  • [6] Georgakilas AG(2005)Low energy electron-driven damage in biomolecules Eur. Phys. J. D 35 367-7994
  • [7] O'Donoghue JA(2000)Resonant formation of DNA strand breaks by low-energy (3 to 20 eV) electrons Science 287 1658-32771
  • [8] Wheldon TE(2002)Mechanism for damage to DNA by low-energy electrons J. Phys. Chem. B 106 7991-1484
  • [9] Mozumder A(2016)Absolute cross-sections for DNA strand breaks and crosslinks induced by low energy electrons Phys. Chem. Chem. Phys. 18 32762-8606
  • [10] Sanche L(2018)Investigation of the radiosensitization effect in FePt nanopaticle clusters with Monte Carlo simulation Nucl. Sci. Tech. 29 167-863