Complexation with C60 Fullerene Increases Doxorubicin Efficiency against Leukemic Cells In Vitro

被引：0
作者：
Anna Grebinyk
Svitlana Prylutska
Sergii Grebinyk
Yuriy Prylutskyy
Uwe Ritter
Olga Matyshevska
Thomas Dandekar
Marcus Frohme
机构：
[1] Technical University of Applied Sciences Wildau,Division Molecular Biotechnology and Functional Genomics
[2] Taras Shevchenko National University of Kyiv,Department of Bioinformatics, Biocenter
[3] University of Würzburg,Institute of Chemistry and Biotechnology
[4] University of Technology Ilmenau,undefined
来源：
Nanoscale Research Letters | 2019年 / 14卷
关键词：
C; fullerene; Doxorubicin; Noncovalent complex; Leukemic cells; Cytotoxicity; Accumulation;
D O I：
暂无
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学科分类号：
摘要：
Conventional anticancer chemotherapy is limited because of severe side effects as well as a quickly evolving multidrug resistance of the tumor cells. To address this problem, we have explored a C60 fullerene-based nanosized system as a carrier for anticancer drugs for an optimized drug delivery to leukemic cells.
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