Complexation with C60 Fullerene Increases Doxorubicin Efficiency against Leukemic Cells In Vitro

被引：0
|
作者：
Anna Grebinyk
Svitlana Prylutska
Sergii Grebinyk
Yuriy Prylutskyy
Uwe Ritter
Olga Matyshevska
Thomas Dandekar
Marcus Frohme
机构：
[1] Technical University of Applied Sciences Wildau,Division Molecular Biotechnology and Functional Genomics
[2] Taras Shevchenko National University of Kyiv,Department of Bioinformatics, Biocenter
[3] University of Würzburg,Institute of Chemistry and Biotechnology
[4] University of Technology Ilmenau,undefined
来源：
Nanoscale Research Letters | 2019年 / 14卷
关键词：
C; fullerene; Doxorubicin; Noncovalent complex; Leukemic cells; Cytotoxicity; Accumulation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Conventional anticancer chemotherapy is limited because of severe side effects as well as a quickly evolving multidrug resistance of the tumor cells. To address this problem, we have explored a C60 fullerene-based nanosized system as a carrier for anticancer drugs for an optimized drug delivery to leukemic cells.
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