Synthesis and biological activity of fluorine-containing amino derivatives based on 4-caranethiol

被引：0
作者：
D. V. Sudarikov
Yu. V. Krymskaya
N. O. Il’chenko
P. A. Slepukhin
S. A. Rubtsova
A. V. Kutchin
机构：
[1] Ural Branch of the Russian Academy of Sciences,Institute of Chemistry, Komi Scientific Center
[2] Ural Branch of the Russian Academy of Sciences,Ya. Postovsky Institute of Organic Synthesis
[3] Ural Federal University named after the First President of Russia B. N. Yeltsin,undefined
来源：
Russian Chemical Bulletin | 2018年 / 67卷
关键词：
4-caranethiol; sulfenimines; sulfinimines; chiral fluorine-containing ; -substituted α-branched sulfinamides; Ruppert–Prakash reagent; fluorine-containing Reformatsky reagent; antimicrobial activity;
D O I：
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中图分类号：
学科分类号：
摘要：
Fluorine-containing N-substituted sulfinamides were synthesized via 4-caranethiol-based sulfenimines and sulfinimines. Stereochemical features of oxidation of sulfenimines and addition of fluorine-containing reagents to sulfinimines were discussed. Antimicrobial activities of the obtained compounds were screened.
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页码：731 / 742
页数：11
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