The Importance of the Individual in PrEP Uptake: Multilevel Correlates of PrEP Uptake Among Adolescent Girls and Young Women in Tshwane, South Africa

被引：0
作者：
Courtney Peasant Bonner
Alexandra M. Minnis
Jacqueline W. Ndirangu
Felicia A. Browne
Ilene Speizer
Laura Nyblade
Khatija Ahmed
Wendee M. Wechsberg
机构：
[1] RTI International,Substance Use, Gender, and Applied Research Program
[2] RTI International,Women’s Global Health Imperative
[3] University of North Carolina at Chapel Hill,Gillings School of Global Public Health
[4] Setshaba Research Centre,Faculty of Health Sciences, Dept of Medical Microbilogy
[5] University of Pretoria,undefined
来源：
AIDS and Behavior | 2023年 / 27卷
关键词：
Adolescent girls and young women; Sub-Saharan Africa; Multilevel factors; PrEP initiation; PrEP uptake; HIV prevention; NCT04048551;
D O I：
暂无
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学科分类号：
摘要：
Adolescent girls and young women (AGYW) account for 25% of new HIV infections in South Africa. Pre-exposure prophylaxis (PrEP) is approved by the South African Government, but the factors that promote PrEP uptake among AGYW are not well understood. This study examines multilevel factors associated with PrEP uptake among AGYW in six clinic catchment areas in Tshwane (Pretoria), South Africa. After consent/assent, PrEP-eligible AGYW (n = 448) completed a questionnaire assessing factors at the individual, network/interpersonal, and community levels and were prescribed PrEP in study clinics, if interested. A multivariable model, adjusting for clustering, assessed factors associated with PrEP uptake over a 9-month period. At the individual level, multiple partners in the past 3 months (OR = 0.47), perceived risk of HIV (OR = 0.71), and PrEP-related shame (OR = 0.63) were correlated with lower odds of PrEP uptake (ps ≤ 0.05). The findings highlight modifiable factors that should be addressed to support PrEP uptake efforts.
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页码：4124 / 4130
页数：6
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