Migraine and white matter hyperintensities

被引:54
作者
Porter A. [1 ]
Gladstone J.P. [1 ]
Dodick D.W. [1 ]
机构
[1] University of Toronto, Division of Neurology, Toronto, Ont. M2J 1V1
关键词
Migraine; White Matter; White Matter Lesion; Migraine With Aura; White Matter Hyperintensities;
D O I
10.1007/s11916-005-0039-y
中图分类号
学科分类号
摘要
Patients with migraine are at increased risk for white matter hyperintensities detected on magnetic resonance imaging. The presence of nonspecific white matter hyperintensities may cause uncertainty for physicians and anxiety for patients. The pathophysiology and long-term consequences of these lesions are unknown. Occasionally, white matter lesions in a migraineur may indicate an underlying disease such as cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS), or central nervous system vasculitis. The ability to distinguish between non-specific and disease-specific patterns of white matter hyperintensities in migraine sufferers is important for the practicing clinician. Copyright © 2005 by Current Science Inc.
引用
收藏
页码:289 / 293
页数:4
相关论文
共 51 条
[1]  
Frishberg B.M., Rosenberg J.H., Matchar D.B., Et al., Evidence-based guidelines in the primary care setting: Neuroimaging in patients with nonacute headache, (2005)
[2]  
Evans R.W., Diagnostic testing for headache, Med. Clin. North Am., 85, pp. 865-885, (2001)
[3]  
Fazekas F., Magnetic resonance signal abnormalities in asymptomatic individuals: Their incidence and functional correlates, Eur. Neurol., 29, pp. 164-168, (1989)
[4]  
Schmidt R., Fazekas F., Kleinert G., Et al., Magnetic resonance imaging signal hyperintensities in the deep and subcortical white matter: A comparative study between stroke patients and normal volunteers, Arch. Neurol., 49, pp. 825-827, (1992)
[5]  
Oyama H., Kida Y., Tanaka T., Incidental white matter lesions identified on magnetic resonance images of normal Japanese individuals: Correlation with age and hypertension, Neurol. Med. Chir. (Tokyo), 34, pp. 286-290, (1994)
[6]  
Ketonen L.M., Neuroimaging of the aging brain, Neurol. Clin., 16, pp. 581-598, (1998)
[7]  
de Groot J.C., de Leeuw F.E., Oudkerk M., Et al., Cerebral white matter lesions and cognitive function: The Rotterdam Scan Study, Ann. Neurol., 47, pp. 145-151, (2000)
[8]  
Manolio T.A., Kronmal R.A., Burke G.L., Et al., Magnetic resonance abnormalities and cardiovascular disease in older adults. The Cardiovascular Health Study, Stroke, 25, pp. 318-327, (1994)
[9]  
Lindgren A., Roijer A., Rudling O., Et al., Cerebral lesions on magnetic resonance imaging, heart disease, and vascular risk factors in subjects without stroke: A population-based study, Stroke, 25, pp. 929-934, (1994)
[10]  
Barkhof F., Scheltens P., Imaging of white matter lesions, Cerebrovas. Dis., 13, SUPPL. 2, pp. 21-30, (2002)