Pan-cancer analysis identifies telomerase-associated signatures and cancer subtypes

被引:0
作者
Zhenhua Luo
Weixu Wang
Feng Li
Zhou Songyang
Xuyang Feng
Changchang Xin
Zhiming Dai
Yuanyan Xiong
机构
[1] School of Life Sciences,Key Laboratory of Gene Engineering of the Ministry of Education and State Key Laboratory of Biocontrol
[2] Sun Yat-Sen University,School of Data and Computer Science
[3] Sun Yat-Sen University,Verna and Marrs Mclean Department of Biochemistry and Molecular Biology
[4] Baylor College of Medicine,Division of Gastroenterology, Hepatology and Nutrition
[5] Cincinnati Children’s Hospital Medical Center and the Department of Pediatrics Cincinnati,Department of Cancer Biology
[6] University of Cincinnati,College of Forestry and Landscape Architecture
[7] South China Agricultural University,The First Affiliated Hospital
[8] Sun Yat-sen University,undefined
来源
Molecular Cancer | / 18卷
关键词
Telomerase; Signature; Survival; Drug target;
D O I
暂无
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学科分类号
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[1]  
O'Sullivan RJ(2010)Telomeres: protecting chromosomes against genome instability Nat Rev Mol Cell Biol 11 171-181
[2]  
Karlseder J(2002)Telomere maintenance and cancer -- look, no telomerase Nat Rev Cancer 2 879-884
[3]  
Neumann AA(1990)Telomeres shorten during ageing of human fibroblasts Nature 345 458-460
[4]  
Reddel RR(1992)The telomere hypothesis of cellular aging Exp Gerontol 27 375-382
[5]  
Harley CB(2009)How telomeres solve the end-protection problem Science 326 948-952
[6]  
Futcher AB(2002)Telomere maintenance as a target for anticancer drug discovery Nat Rev Drug Discov 1 383-393
[7]  
Greider CW(2001)Telomere maintenance by telomerase and by recombination can coexist in human cells Hum Mol Genet 10 1945-1952
[8]  
Harley CB(2012)Telomerase directly regulates NF-kappaB-dependent transcription Nat Cell Biol 14 1270-1281
[9]  
Vaziri H(2011)Maintenance of tumor initiating cells of defined genetic composition by nucleostemin Proc Natl Acad Sci U S A 108 20388-20393
[10]  
Counter CM(2009)Telomerase modulates Wnt signalling by association with target gene chromatin Nature 460 66-72