Population pharmacokinetics of levodopa/carbidopa microtablets in healthy subjects and Parkinson’s disease patients

[1] Senek M(2014)Continuous drug delivery in Parkinson’s disease CNS Drugs 28 19-27

[2] Nyholm D(2012)Pharmacokinetics of levodopa/carbidopa microtablets versus levodopa/benserazide and levodopa/carbidopa in healthy volunteers Clin Neuropharmacol 35 111-117

[3] Nyholm D(2013)Frequent administration of levodopa/carbidopa microtablets vs levodopa/carbidopa/entacapone in healthy volunteers Acta Neurol Scand 127 124-132

[4] Lewander T(2003)An automatic dose dispenser for microtablets—a new concept for individual dosage of drugs in tablet form Int J Pharm 261 137-146

[5] Gomes-Trolin C(2017)First clinical experience with levodopa/carbidopa microtablets in Parkinson’s disease Acta Neurol Scand 136 727-731

[6] Bäckström T(1997)Pharmacodynamics of benserazide assessed by its effects on endogenous and exogenous levodopa pharmacokinetics Br J Clin Pharmacol 44 41-48

[7] Panagiotidis G(1981)A specific radioenzymatic assay for dihydroxyphenylalanine (DOPA). Plasma dopa may be the precursor of urine free dopamine Br J Clin Pharmacol 11 79-83

[8] Ehrnebo M(2017)Elucidation of factor VIII activity pharmacokinetics: a pooled population analysis in patients with hemophilia a treated with moroctocog alfa Clin Pharmacol Ther 102 977-988

[9] Nyström C(2017)Population pharmacokinetic analysis of vaginally and intravenously administered oxytocin in postmenopausal women J Clin Pharmacol 57 1573-1581

[10] Aquilonius SM(2007)Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies J Pharmacokinet Pharmacodyn 34 711-726

[1] Senek M(2014)Continuous drug delivery in Parkinson’s disease CNS Drugs 28 19-27

[2] Nyholm D(2012)Pharmacokinetics of levodopa/carbidopa microtablets versus levodopa/benserazide and levodopa/carbidopa in healthy volunteers Clin Neuropharmacol 35 111-117

[3] Nyholm D(2013)Frequent administration of levodopa/carbidopa microtablets vs levodopa/carbidopa/entacapone in healthy volunteers Acta Neurol Scand 127 124-132

[4] Lewander T(2003)An automatic dose dispenser for microtablets—a new concept for individual dosage of drugs in tablet form Int J Pharm 261 137-146

[5] Gomes-Trolin C(2017)First clinical experience with levodopa/carbidopa microtablets in Parkinson’s disease Acta Neurol Scand 136 727-731

[6] Bäckström T(1997)Pharmacodynamics of benserazide assessed by its effects on endogenous and exogenous levodopa pharmacokinetics Br J Clin Pharmacol 44 41-48

[7] Panagiotidis G(1981)A specific radioenzymatic assay for dihydroxyphenylalanine (DOPA). Plasma dopa may be the precursor of urine free dopamine Br J Clin Pharmacol 11 79-83

[8] Ehrnebo M(2017)Elucidation of factor VIII activity pharmacokinetics: a pooled population analysis in patients with hemophilia a treated with moroctocog alfa Clin Pharmacol Ther 102 977-988

[9] Nyström C(2017)Population pharmacokinetic analysis of vaginally and intravenously administered oxytocin in postmenopausal women J Clin Pharmacol 57 1573-1581

[10] Aquilonius SM(2007)Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies J Pharmacokinet Pharmacodyn 34 711-726