Plasma leptin concentrations and four-year weight gain among US men

被引：0
作者：
N-F Chu
D Spiegelman
J Yu
N Rifai
GS Hotamisligil
EB Rimm
机构：
[1] Harvard School Public Health,Department of Epidemiology
[2] Tri-Service General Hospital,Departments of Public Health and Community Medicine
[3] National Defense Medical Center,Department of Biostatistics
[4] Harvard School Public Health,Department of Nutrition
[5] Harvard School Public Health,Department of Laboratory Medicine
[6] Children's Hospital,Department of Pathology
[7] Harvard Medical School,Division of Biological Science
[8] Harvard School Public Health,Department of Medicine
[9] Channing Laboratory,undefined
[10] Harvard Medical School and Brigham and Women's Hospital,undefined
来源：
International Journal of Obesity | 2001年 / 25卷
关键词：
leptin; weight gain; men;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
OBJECTIVE: Leptin, a primarily adipose tissue-derived protein product of the obesity (ob) gene, is an important regulator of energy metabolism. The strong association between body fat mass and elevated circulating leptin levels in humans suggests that leptin resistance, rather than leptin production, may contribute to the development of obesity and associated disorders. The purpose of this study is to evaluate the relationship between circulating plasma leptin levels and regulation of body weight over time among US men.
引用
收藏
页码：346 / 353
页数：7
相关论文
共 181 条
[41]  
Spiegelman BM(1992)Validity of self-reported waist and hip circumferences in men and women Am J Epidemiol 135 1114–1126. [Discussion 1127-1136.]
[42]  
Flier JS(1999)The assessment of alcohol consumption by a simple self-administered questionnaire Clin Biochem 32 87-89
[43]  
Zimmet P(1996)Reproducibility and validity of a self-administered physical activity questionnaire for male health professionals Clin Chem 42 942-946
[44]  
Hodge A(1995)Reproducibility and validity of an expanded self-administered semiquantitative food frequency questionnaire among male health professionals Diabetes 44 1467-1470
[45]  
Nicolson M(1997)Stability of human plasma leptin concentrations with 36 hours following specimen collection J Clin Endocrinol Metab 82 3408-3413
[46]  
Weigle DS(1998)Radioimmunoassay of leptin in human plasma Obes Res 6 179-186
[47]  
Flier JS(1997)The Ann Epidemiol 7 81-86
[48]  
Friedman JM(1996) gene and insulin. A relationship leading to clues to the understanding of obesity J Clin Endocrinol Metab 81 3424-3427
[49]  
Auwerx J(1998)Leptin concentrations in relation to body mass index and the tumor necrosis factor-alpha system in humans J Clin Endocrinol Metab 83 931-934
[50]  
Staels B(1996)Circulating insulin concentrations, smoking, and alcohol intake are important independent predictors of leptin in young healthy men Horm Metab Res 28 698-703
12345678910