Cardiac sarcoidosis: Update 2017

被引：0

作者：

Skowasch D. ^{[1
]}

Grohé C. ^{[2
]}

Pizarro C. ^{[1
]}

机构：

[1] Medizinische Klinik und Poliklinik II – Sektion Pneumologie, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, Bonn

[2] Klinik für Pneumologie, Evangelische Lungenklinik Berlin Buch, Berlin

来源：

Der Pneumologe | 2018年 / 15卷 / 2期

关键词：

Boeck disease; Cardiomyopathies; Granulomatosis; Myocardial diseases; Pulmonary hypertension;

D O I：

10.1007/s10405-017-0155-5

中图分类号：

学科分类号：

摘要：

Sarcoidosis is a granulomatous disease of unknown etiology. Cardiac sarcoidosis is reported in OpenSPiltSPi10% of patients with sarcoidosis and is associated with a substantially poorer prognosis. As a rule the clinical manifestations are atrioventricular block, ventricular tachycardia and/or heart failure. Screening should comprise an electrocardiogram (ECG), Holter (long-term) monitoring and echocardiography. For extended diagnostics cardiac magnetic resonance imaging (MRI), positron emission tomography/computed tomography (PET/CT) and myocardial biopsy can be useful. Immunosuppression with steroids and heart failure medication are the therapeutic cornerstones. Non-pharmacological options are the implantation of a pacemaker, an implantable cardioverter-defibrillator (ICD) and catheter ablation. Due to the low body of evidence, diagnostic and therapeutic procedures must be adapted to the individual patient situation. © 2017, Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

引用

页码：75 / 80

页数：5

共 25 条

[1]

Pabst S., Skowasch D., Grohe C., Sarkoidose, Pneumologie, 66, pp. 96-110, (2012)

[2]

Pizarro C., Skowasch D., Grohe C., Aktuelle Therapieansätze der Sarkoidose, Dtsch Med Wochenschr, 142, pp. 17-23, (2017)

[3]

Costabel U., Skowasch D., Pabst S., Et al., Konsensuspapier der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin (DGP) und der Deutschen Gesellschaft für Kardiologie – Herz und Kreislaufforschung (DGK) zur Diagnostik und Therapie der kardialen Sarkoidose, Pneumologie, 68, pp. 124-132, (2014)

[4]

Birnie D.H., Sauer W.H., Bogun F., Et al., Expert consensus statement on the diagnosis and management of arrhythmias associated with cardiac sarcoidosis, Heart Rhythm, 7, pp. 1305-1323, (2014)

[5]

Kusano K.F., Satomi K., Diagnosis and treatment of cardiac sarcoidosis, Heart, 201, pp. 184-190, (2016)

[6]

Gideon N.M., Mannino D.M., Sarcoidosis mortality in the United States 1979–1991: an analysis of multiple-cause mortality data, Am J Med, 100, pp. 423-427, (1996)

[7]

Tuleta I., Pingel S., Biener I., Et al., Atherosclerotic vessel changes in sarcoidosis, Adv Exp Med Biol, 910, pp. 23-30, (2016)

[8]

Pizarro C., Goebel A., Dabir D., Et al., Cardiovascular magnetic resonance-guided diagnosis of cardiac affection in a caucasian sarcoidosis population, Sarcoidosis Vasc. Diffuse Lung. Dis., 32, pp. 325-335, (2015)

[9]

Kandolin R., Lehtonen J., Kupari M., Cardiac sarcoidosis and giant cell myocarditis as causes of atrioventricular block in young and middle-aged adults, Circ Arrhythm Electrophysiol, 4, pp. 303-309, (2011)

[10]

Smedana J.P., Snoep G., van Kroonenburgh M.P., Et al., Cardiac involvement in patients with pulmonary sarcoidosis at two university medical centers in Netherlands, Chest, 128, pp. 30-35, (2005)

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