Complexin and Ca2+ stimulate SNARE-mediated membrane fusion

被引:0
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作者
Tae-Young Yoon
Xiaobing Lu
Jiajie Diao
Soo-Min Lee
Taekjip Ha
Yeon-Kyun Shin
机构
[1] Howard Hughes Medical Institute,Department of Physics
[2] University of Illinois at Urbana-Champaign,Department of Biochemistry
[3] University of Illinois at Urbana-Champaign,undefined
[4] Biophysics,undefined
[5] and Molecular Biology,undefined
[6] Iowa State University,undefined
[7] Present address: Department of Physics and KAIST Institute for the BioCentury,undefined
[8] KAIST,undefined
[9] 373-1 Guseong-dong,undefined
[10] Yuseong-gu,undefined
[11] Daejeon 305-701,undefined
[12] Korea.,undefined
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摘要
Complexin is one of several regulatory molecules known to be important for SNARE-mediated fusion that occurs during neurotransmitter release. In vitro data now suggest that complexin plays inhibitory and Ca2+- dependent stimulatory roles that may be correlated to changing interactions with the SNARE complex.
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页码:707 / 713
页数:6
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