Mediastinal histoplasmosis presenting as dysphagia: A case report with literature review

被引：8

作者：

Chaudhari D. ^{[1
]}

McKinney J. ^{[2
]}

Hubbs D. ^{[1
]}

Young M. ^{[2
]}

机构：

[1] Department of Internal Medicine, East Tennessee State University, Johnson City, TN 37615, 1008 Quality Circle

[2] Department of Gastroenterology, East Tennessee State University, Johnson City, TN

来源：

Clinical Journal of Gastroenterology | 2013年 / 6卷 / 4期

关键词：

Dysphagia; Histoplasma; Mediastinal histoplasmosis; Mediastinal lymphadenopathy;

D O I：

10.1007/s12328-013-0405-y

中图分类号：

学科分类号：

摘要：

Histoplasmosis is an endemic infection of the Ohio and Mississippi River valleys. Clinical presentation of infection in immunocompetent hosts ranges from asymptomatic to minor flu-like symptoms; however, disseminated infection can occur in immunocompromised patients. Esophageal involvement in the form of dysphagia secondary to mediastinal histoplasmosis is rarely reported in the literature. We present a young female who complained of dysphagia and was found to have an esophageal stricture on barium esophagogram. Endoscopy revealed a submucosal nodule stricture situated 29 cm from the incisors. She underwent thoracotomy for lymph node removal. Histologic findings of the removed lymph node showed caseating granuloma with macrophages. The clinical findings together with the laboratory evaluation and biopsy features were suggestive of mediastinal histoplasmosis as the cause of the dysphagia. © 2013 Springer Japan.

引用

页码：315 / 318

页数：3

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