Probiotics and food allergy

被引:0
作者
Anna Maria Castellazzi
Chiara Valsecchi
Silvia Caimmi
Amelia Licari
Alessia Marseglia
Maria Chiara Leoni
Davide Caimmi
Michele Miraglia del Giudice
Salvatore Leonardi
Mario La Rosa
Gian Luigi Marseglia
机构
[1] University of Pavia,Department of Pediatrics, Foundation IRCCS Policlinico San Matteo
[2] Second University of Naples,Department of Pediatrics
[3] University of Catania,Department of Medical and Pediatric Science
来源
Italian Journal of Pediatrics | / 39卷
关键词
Food allergy; Probiotics; Allergic disease; Intestinal microbiota; Children;
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摘要
The exact prevalence of food allergy in the general population is unknown, but almost 12% of pediatric population refers a suspicion of food allergy. IgE mediated reactions to food are actually the best-characterized types of allergy, and they might be particularly harmful especially in children. According to the “hygiene hypothesis” low or no exposure to exogenous antigens in early life may increase the risk of allergic diseases by both delaying the development of the immune tolerance and limiting the Th2/Th1 switch. The critical role of intestinal microbiota in the development of immune tolerance improved recently the interest on probiotics, prebiotics, antioxidants, polyunsaturated fatty acid, folate and vitamins, which seem to have positive effects on the immune functions.
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