Microextraction of bioactive compounds using deep eutectic solvents: a review

被引:0
作者
Lamia Nakhle
Miriana Kfoury
Isabelle Mallard
David Landy
Hélène Greige-Gerges
机构
[1] Lebanese University,Bioactive Molecules Research Laboratory, Doctoral School of Sciences and Technologies, Faculty of Sciences
[2] Université du Littoral Côte d’Opale (ULCO),Unité de Chimie Environnementale et Interactions sur le Vivant (UCEIV, EA 4492), SFR Condorcet FR CNRS 3417
来源
Environmental Chemistry Letters | 2021年 / 19卷
关键词
Bioactive compounds; Combined extraction techniques; Deep eutectic solvents; Green chemistry; Liquid–liquid-phase microextraction; Physicochemical properties; Proteins; Solid-phase microextraction;
D O I
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中图分类号
学科分类号
摘要
Analytical scientists are actually developing sustainable methods for the analysis of environmental samples. In particular, replacing classical, toxic solvents by safer solvents is a principle of green chemistry. For instance, deep eutectic solvents, formed by mixing two or more components by hydrogen bonding, appear promising. Here, we review the use of deep eutectic solvents for liquid–liquid, liquid–solid and combined extractions. We compare the use of deep eutectic solvents with conventional organic solvents for extraction. Overall, deep eutectic solvents showed better extraction efficiency and higher recovery compared to water and conventional organic solvents. In particular, deep eutectic solvents showed about 93–99% efficiency for protein extraction. The extraction efficiency often depends on the physicochemical properties of deep eutectic solvents.
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页码:3747 / 3759
页数:12
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