Reconstitution of Secreted Frizzled-Related Protein 1 Suppresses Tumor Growth and Lung Metastasis in an Orthotopic Model of Hepatocellular Carcinoma

被引：0
作者：
Gui-Xing Jiang
Wei Liu
Yun-Fu Cui
Xiang-Yu Zhong
Sheng Tai
Zhi-Dong Wang
Yu-Guang Shi
Chun-Long Li
Shi-Yong Zhao
机构：
[1] Second Affiliated Hospital of Harbin Medical University,Department of Hepatopancreatobiliary Surgery
[2] Second Affiliated Hospital of Harbin Medical University,Laboratory of Molecular Biology
来源：
Digestive Diseases and Sciences | 2010年 / 55卷
关键词：
Secreted Frizzled-related protein 1 (sFRP1); Hepatocellular carcinoma (HCC); Growth; Metastasis; β-Catenin;
D O I：
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学科分类号：
摘要：
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页码：2838 / 2843
页数：5
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共 109 条
  • [1] Kouzmenko AP(2004)Wnt/beta-catenin and estrogen signaling converge in vivo J Biol Chem 279 40255-40258
  • [2] Takeyama K(1996)Signal transduction through beta-catenin and specification of cell fate during embryogenesis Genes Dev 10 2527-2539
  • [3] Ito S(2009)Nusse R.Towards an integrated view of Wnt signaling in development Development 136 3205-3214
  • [4] Miller JR(1999)The control of beta-catenin and TCF during embryonic development and cancer Cancer Metastasis Rev 18 231-246
  • [5] Moon RT(2004)WNT and beta-catenin signalling: Diseases and therapies Nat Rev Genet 5 691-701
  • [6] van Amerongen R(2000)Wnt signaling and cancer Genes Dev 14 1837-1851
  • [7] Waltzer L(2004)Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer Nat Genet 36 417-422
  • [8] Bienz M(1999)Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells Nature 398 422-426
  • [9] Moon RT(2007)WNT signaling pathway and stem cell signaling network Clin Cancer Res 13 4042-4045
  • [10] Kohn AD(2006)Promoter methylation of the secreted frizzled-related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma Cancer 107 579-590
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