MPEG-b-poly(amino urethane) amphiphilic block copolymers and their pH-Dependent micellization behavior

被引:0
作者
Kasala Dayananda
Chaoliang He
Ying Qian Hu
Min Sang Kim
Doo Sung Lee
机构
[1] Sungkyunkwan University,Polymer Technology Institute
[2] Sungkyunkwan University,Department of Polymer Science and Engineering
来源
Macromolecular Research | 2009年 / 17卷
关键词
Pyrene; Block Copolymer; Dynamic Light Scattering; Triblock Copolymer; Polymeric Micelle;
D O I
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中图分类号
学科分类号
摘要
The MPEG-PAU block coplymers were successfully synthesized and their chemical structures were well characterized by1H,13C NMR and FT-IR spectroscopies. The aqueous solution properties of the copolymers were evaluated by acid-base titration, fluorescence spectroscopy and dynamic light scattering. The block copolymers exhibited a pHdependent micellization-demicellization transition in aqueous solution. The fluorescence spectroscopy and DLS measurements indicate that the micellization-demicellization transition occurs at pH 6.0–6.6. The amphiphilic block copolymers are expected to find applications in biomedical field.
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页码:58 / 61
页数:3
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