Prevalence of abnormal lactose breath hydrogen tests in children with functional abdominal pain

被引:5
作者
Garg N. [1 ]
Basu S. [1 ]
Singh P. [1 ]
Kumar R. [1 ]
Sharma L. [1 ]
Kumar P. [1 ]
机构
[1] Department of Pediatrics, Lady Hardinge Medical College, C-604, Shaheed Bhagat Singh Road, Diz Area, Connaught Place, New Delhi
关键词
Hydrogen breath tests; Recurrent acute pancreatitis; Small intestinal bacterial overgrowth;
D O I
10.1007/s12664-017-0750-8
中图分类号
学科分类号
摘要
Objectives: The study was undertaken to determine the prevalence of abnormal lactose breath hydrogen test in children with non-organic chronic abdominal pain. Methods: Children with chronic abdominal pain were examined and investigated for organic causes. All children without a known organic cause underwent lactose and glucose breath hydrogen test. After a standard dose of 2 g/kg of lactose to a maximum of 50 g, hydrogen in breath was measured at 15 min intervals for 3 h. A rise of 20 ppm above baseline was considered suggestive of lactose malabsorption. Results: Of 108 children screened, organic causes were found in 46 children. Sixty-two patients without any organic cause underwent hydrogen breath test. Lactose hydrogen breath test (HBT) was positive in 36 of 62 (58%), while 11 (17%) had positive HBT with glucose suggestive of small intestinal bacterial overgrowth (SIBO). Twenty out of 34 (59%) improved on lactose free diet while 8 out of 11 (72%) children of SIBO improved on antibiotics. Conclusions: Lactose malabsorption was seen in 58% of children with non-organic chronic abdominal pain. © 2017, Indian Society of Gastroenterology.
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页码:179 / 183
页数:4
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