Peroxisome proliferator-activated receptor γ ligand inhibits cell growth and invasion of human pancreatic cancer cells

被引:0
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作者
Koji Hashimoto
Richard T. Ethridge
B. Mark Evers
机构
[1] The University of Texas Medical Branch,Department of Surgery
关键词
Pancreatic cancer; peroxisome proliferator-activated receptor ; cell cycle; apoptosis; tumor invasion;
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学科分类号
摘要
Background. Peroxisome proliferator-activated receptor γ (PPARγ) is expressed in certain human cancers; ligand-induced PPARγ activation can result in growth inhibition and differentiation in these cells. However, the precise mechanism for the antiproliferative effect of PPARγ ligands is not entirely known.
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页码:7 / 22
页数:15
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