Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells

被引：0
|
作者：
Tom Cupedo
Natasha K Crellin
Natalie Papazian
Elwin J Rombouts
Kees Weijer
Jane L Grogan
Willem E Fibbe
Jan J Cornelissen
Hergen Spits
机构：
[1] Erasmus University Medical Center,Department of Hematology
[2] Academic Medical Center of the University of Amsterdam,Department Cell Biology and Histology
[3] Genentech Inc.,Department of Immunology
[4] Leiden University Medical Center,Department of Immunohematology and Blood Transfusion
来源：
Nature Immunology | 2009年 / 10卷
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摘要：
Mouse lymphoid tissue–inducer (LTi) cells require the transcription factor RORγt. Cupedo's group identifies RORγt+ human LTi cell equivalents as committed natural killer cell precursors, and teams led by Vivier and Diefenbach describe RORγt-expressing interleukin 22–producing natural killer cells in mouse gut.
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页码：66 / 74
页数：8
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