Astrovirus enteritis in a chronic lymphocytic leukemia patient treated with fludarabine monophosphate

被引:0
作者
P. Coppo
C. Scieux
F. Ferchal
J. -P. Clauvel
K. Lassoued
机构
[1] Service d'Immuno-Hématologie,
[2] Hôpital Saint-Louis,undefined
[3] Paris,undefined
[4] France e-mail: kaiss.lassoued@sa.u-picardie.fr Tel: 0033-1-4249-9690 Fax: 0033-1-4249-9472,undefined
[5] Laboratoire de Virologie-Bactériologie,undefined
[6] Hôpital Saint-Louis,undefined
[7] 1,undefined
[8] Avenue Claude Vellefaux,undefined
[9] F-75475 Paris cedex 10,undefined
[10] France,undefined
来源
Annals of Hematology | 2000年 / 79卷
关键词
Key words Astrovirus; Enteric infection; Chronic lymphocytic leukemia; Purine analogues; Fludarabine monophosphate;
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摘要
 We report on a case of severe astrovirus gastroenteritis in a chronic lymphocytic leukemia (CLL) patient treated with fludarabine monophosphate (FAMP). Astrovirus was detected in stools using both an immunoenzymatic assay and an electronic microscopy analysis. Treatment consisted in symptomatic care and the outcome was favorable. Astrovirus infection might constitute a common etiology of gastroenteritis in patients with hematologic malignancies that have been severely immunocompromised with FAMP or other purine analogues, and therefore should be more systematically investigated.
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页码:43 / 45
页数:2
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