Cell apoptosis induced by carcinogenic metals

被引：1
作者：
Fei Chen
Val Vallyathan
Vince Castranova
Xianglin Shi
机构：
[1] National Institute for Occupational Safety and Health,Health Effects Laboratory Division
来源：
Molecular and Cellular Biochemistry | 2001年 / 222卷
关键词：
apoptosis; metal; ROS; DNA damage; carcinogenesis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Well-documented evidence suggests that environmental and occupational exposure of toxic metals or metal-containing compounds can cause a number of human diseases, including inflammation and cancer, through DNA damage, protein modifications, or lipid peroxidation. This mini-review addresses the mechanisms of cell death induced by some carcinogenic metals, including arsenic (III), chromium (VI) and vanadium (V). A possible contribution of reactive oxygen species to metal-induced cell death is also discussed.
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页码：183 / 188
页数：5
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