Water-Soluble and Low Molecular Weight Chitosan-Based Plasmid DNA Delivery

被引：0
作者：
Minhyung Lee
Jae-Woon Nah
Youngmin Kwon
Jae Joon Koh
Kyung Soo Ko
Sung Wan Kim
机构：
[1] University of Utah,Department of Pharmaceutics and Pharmaceutical Chemistry, Center for Controlled Chemical Delivery
[2] Sunchon National University,Department of Polymer Science and Engineering
[3] Inje University,Department of Internal Medicine, College of Medicine
来源：
Pharmaceutical Research | 2001年 / 18卷
关键词：
DNase I; gel retardation; gene delivery; transfection; low molecular weight chitosan (LMWC); MTT assay;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. Chitosan, a natural cationic polysaccharide, is a candidate non-viral vector for gene delivery because of its high positive charges and low cytotoxicity. In this study, low molecular weight chitosan (LMWC, molecular weight of 22 kDa) was characterized and evaluated as a gene carrier.
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页码：427 / 431
页数：4
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