Association between dual sensory impairment and risk of mortality: a cohort study from the UK Biobank (vol 22, 631, 2022)

被引：0

作者：

Zhang, Xinyu ^{[1
,2
]}

Wang, Yueye ^{[1
]}

Wang, Wei ^{[3
]}

Hu, Wenyi ^{[4
]}

Shang, Xianwen ^{[1
]}

Liao, Huan ^{[5
]}

Chen, Yifan ^{[6
]}

Kiburg, Katerina V. ^{[4
]}

Huang, Yu ^{[1
]}

Zhang, Xueli ^{[1
]}

Tang, Shulin ^{[1
]}

Yu, Honghua ^{[1
]}

Yang, Xiaohong ^{[1
]}

He, Mingguang ^{[1
,3
,4
]}

Zhu, Zhuoting ^{[1
,4
]}

机构：

[1] Guangdong Acad Med Sci, Guangdong Prov Peoples Hosp, Dept Ophthalmol, Guangzhou, Peoples R China

[2] Shanghai Gen Hosp, Dept Ophthalmol, Shanghai, Peoples R China

[3] Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, Guangzhou, Peoples R China

[4] Univ Melbourne, Ctr Eye Res, East Melbourne, Vic, Australia

[5] Univ Bonn, Inst Reconstruct Neurobiol, Neural Regenerat Grp, Bonn, Germany

[6] Oxford Univ Hosp NHS Fdn Trust, John Radcliffe Hosp, Oxford, England

来源：

BMC GERIATRICS | 2022年 / 22卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Hearing impairment; Mortality; Sensory impairment; UK Biobank; Visual impairment;

D O I：

10.1186/s12877-022-03384-x

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Background: Dual sensory impairment is affecting over 10% of older adults worldwide. However, the long-term effect of dual sensory impairment (DSI) on the risk of mortality remains controversial. We aim to investigate the impact of single or/and dual sensory impairment on the risk of mortality in a large population-based sample of the adult in the UK with 14-years of follow-up. Methods: This population-based prospective cohort study included participants aged 40 and over with complete records of visual and hearing functions from the UK Biobank study. Measurements of visual and hearing functions were performed at baseline examinations between 2006 and 2010, and data on mortality was obtained by 2021. Dual sensory impairment was defined as concurrent visual and hearing impairments. Cox proportional hazards regression models were employed to evaluate the impact of sensory impairment (dual sensory impairment, single visual or hearing impairment) on the hazard of mortality. Results: Of the 113,563 participants included in this study, the mean age (standard deviation) was 56.8 (8.09) years, and 61,849 (54.5%) were female. At baseline measurements, there were 733 (0.65%) participants with dual sensory impairment, 2,973 (2.62%) participants with single visual impairment, and 13,560 (11.94%) with single hearing impairment. After a follow-up period of 14 years (mean duration of 11 years), 5,992 (5.28%) participants died from all causes. Compared with no sensory impairment, dual sensory impairment was significantly associated with an estimated 44% higher hazard of mortality (hazard ratio: 1.44 [95% confidence interval, 1.11–1.88], p = 0.007) after multiple adjustments. Conclusions: Individuals with dual sensory impairment were found to have an independently 44% higher hazard of mortality than those with neither sensory impairment. Timely intervention of sensory impairment and early prevention of its underlying causes should help to reduce the associated risk of mortality. © 2022, The Author(s).

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