COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup

被引：465

作者：

Nadim, Mitra K. ^{[1
]}

Forni, Lui C. ^{[2
,3
]}

Mehta, Ravindra L. ^{[4
]}

Connor, Michael J., Jr. ^{[5
,6
,7
,8
]}

Liu, Kathleen D. ^{[9
,10
,11
,12
]}

Ostermann, Marlies ^{[13
]}

Rimmele, Thomas ^{[14
]}

Zarbock, Alexander ^{[15
]}

Bell, Samira ^{[16
]}

Bihorac, Azra ^{[17
]}

Cantaluppi, Vincenzo ^{[18
]}

Hoste, Eric ^{[19
]}

Husain-Syed, Faeq ^{[20
]}

Germain, Michael J. ^{[21
]}

Goldstein, Stuart L. ^{[22
]}

Gupta, Shruti ^{[23
]}

Joannidis, Michael ^{[24
]}

Kashani, Kianoush ^{[25
]}

Koyner, Jay L. ^{[26
]}

Legrand, Matthieu ^{[27
]}

Lumlertgul, Nuttha ^{[13
,28
]}

Mohan, Sumit ^{[29
,30
,31
]}

Pannu, Neesh ^{[32
]}

Peng, Zhiyong ^{[33
]}

Perez-Fernandez, Xose L. ^{[34
]}

Pickkers, Peter ^{[35
]}

Prowle, John ^{[36
]}

Reis, Thiago ^{[37
,38
]}

Srisawat, Nattachai ^{[28
,39
]}

Tolwani, Ashita ^{[40
]}

Vijayan, Anitha ^{[41
]}

Villa, Gianluca ^{[42
]}

Yang, Li ^{[43
]}

Ronco, Claudio ^{[37
,44
]}

Kellum, John A. ^{[45
]}

机构：

[1] Univ Southern Calif, Keck Sch Med, Dept Med, Div Nephrol & Hypertens, Los Angeles, CA 90007 USA

[2] Univ Surrey, Fac Hlth Sci, Dept Clin & Expt Med, Guildford, Surrey, England

[3] Royal Surrey Cty Hosp NHS Fdn Trust, Intens Care Unit, Guildford, Surrey, England

[4] Univ Calif San Diego, Dept Med, Div Nephrol, San Diego, CA 92103 USA

[5] Emory Univ, Sch Med, Dept Med, Div Renal Med,Div Pulm, Atlanta, GA USA

[6] Emory Univ, Sch Med, Dept Med, Div Renal Med,Div Allergy, Atlanta, GA USA

[7] Emory Univ, Sch Med, Dept Med, Div Renal Med,Div Crit Care, Atlanta, GA USA

[8] Emory Univ, Sch Med, Dept Med, Div Renal Med,Div Sleep Med, Atlanta, GA USA

[9] Univ Calif San Francisco, Dept Med, Div Nephrol, San Francisco, CA 94143 USA

[10] Univ Calif San Francisco, Dept Med, Div Crit Care Med, San Francisco, CA 94143 USA

[11] Univ Calif San Francisco, Dept Anesthesia, Div Nephrol, San Francisco, CA USA

[12] Univ Calif San Francisco, Dept Anesthesia, Div Crit Care Med, San Francisco, CA USA

[13] Guys & St Thomas NHS Fdn Hosp, Dept Intens Care, London, England

[14] Hosp Civils Lyon, Edouard Herriot Hosp, Dept Anesthesiol & Intens Care Med, Lyon, France

[15] Univ Hosp Munster, Dept Anesthesiol Intens Care & Pain Med, Munster, Germany

[16] Univ Dundee, Sch Med, Div Populat Hlth & Genom, Dundee, Scotland

[17] Univ Florida, Dept Med, Gainesville, FL USA

[18] Univ Piemonte Orientate, Dept Translat Med, Nephrol & Kidney Transplantat Unit, Novara, Italy

[19] Univ Ghent, Ghent Univ Hosp, Intens Care Unit, Ghent, Belgium

[20] Univ Hosp Giessen & Marburg, Dept Med 2, Div Nephrol Pulmonol & Crit Care Med, Giessen, Germany

[21] Baystate Med Ctr U Mass Med Sch, Renal Transplant Associates New England, Div Nephrol, Springfield, MA USA

[22] Cincinnati Childrens Hosp Med Ctr, Div Nephrol & Hypertens, Cincinnati, OH 45229 USA

[23] Brigham & Womens Hosp, Div Renal Med, 75 Francis St, Boston, MA 02115 USA

[24] Med Univ Innsbruck, Dept Med, Div Intens Care & Emergency Med, Innsbruck, Austria

[25] Mayo Clin, Dept Med, Div Pulm & Crit Care Med, Div Nephrol & Hypertens, Rochester, MN USA

[26] Univ Chicago, Dept Med, Div Nephrol, 5841 S Maryland Ave, Chicago, IL 60637 USA

[27] Univ Calif San Francisco, Dept Anesthesiol & Perioperat Care, San Francisco, CA 94143 USA

[28] Chulalongkorn Univ, King Chulalongkorn Mem Hosp, Crit Care Nephrol Res Unit, Div Nephrol,Excellence Ctr Crit Care Nephrol, Bangkok, Thailand

[29] Columbia Univ Coll Phys & Surg, Dept Med, Div Nephrol, New York, NY USA

[30] New York Presbyterian Hosp, New York, NY USA

[31] Columbia Univ, Mailman Sch Publ Hlth, Dept Epidemiol, New York, NY USA

[32] Univ Alberta, Fac Med & Dent, Div Crit Care Med, Edmonton, AB, Canada

[33] Wuhan Univ, Zhongnan Hosp, Div Crit Care Med, Wuhan, Peoples R China

[34] Hosp Univ Bellvitge, Serv Med Intens, Barcelona, Spain

[35] Radboudumc, Dept Intens Care Med, Nijmegen, Netherlands

[36] Queen Mary Univ London, William Harvey Res Inst, Crit Care & Pert Operat Med Res Grp, London, England

[37] San Bortolo Hosp, Int Renal Res Inst Vicenza, Dept Nephrol Dialysis & Transplantat, Vicenza, Italy

[38] Clin Doencas Renais Brasilia, Dept Nephrol, Brasilia, DF, Brazil

[39] Royal Soc Thailand, Acad Sci, Bangkok, Thailand

[40] Univ Alabama Birmingham, Dept Med, Div Nephrol, Birmingham, AL 35294 USA

[41] Washington Univ, Sch Med, Div Nephrol, St Louis, MO USA

[42] Univ Florence, Dept Hlth Sci, Sect Anaesthesiol & Intens Care, Florence, Italy

[43] Peking Univ First Hosp, Renal Div, Beijing, Peoples R China

[44] Univ Padua, Dept Med, Padua, Italy

[45] Univ Pittsburgh, Ctr Crit Care Nephrol, Dept Crit Care Med, Pittsburgh, PA 15260 USA

来源：

NATURE REVIEWS NEPHROLOGY | 2020年 / 16卷 / 12期

关键词：

RENAL-REPLACEMENT THERAPY; CRITICALLY-ILL PATIENTS; POLYMYXIN-B HEMOPERFUSION; NEW-YORK-CITY; SEPTIC SHOCK; BALANCED CRYSTALLOIDS; HOSPITALIZED-PATIENTS; PERITONEAL-DIALYSIS; COVID-19; CORONAVIRUS;

D O I：

10.1038/s41581-020-00356-5

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Kidney involvement in patients with coronavirus disease 2019 (COVID-19) is common, and can range from the presence of proteinuria and haematuria to acute kidney injury (AKI) requiring renal replacement therapy (RRT; also known as kidney replacement therapy). COVID-19-associated AKI (COVID-19 AKI) is associated with high mortality and serves as an independent risk factor for all-cause in-hospital death in patients with COVID-19. The pathophysiology and mechanisms of AKI in patients with COVID-19 have not been fully elucidated and seem to be multifactorial, in keeping with the pathophysiology of AKI in other patients who are critically ill. Little is known about the prevention and management of COVID-19 AKI. The emergence of regional 'surges' in COVID-19 cases can limit hospital resources, including dialysis availability and supplies; thus, careful daily assessment of available resources is needed. In this Consensus Statement, the Acute Disease Quality Initiative provides recommendations for the diagnosis, prevention and management of COVID-19 AKI based on current literature. We also make recommendations for areas of future research, which are aimed at improving understanding of the underlying processes and improving outcomes for patients with COVID-19 AKI.

引用

页码：747 / 764

页数：18

共 140 条

[1] Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19 [J].

Ackermann, Maximilian ;

Verleden, Stijn E. ;

Kuehnel, Mark ;

Haverich, Axel ;

Welte, Tobias ;

Laenger, Florian ;

Vanstapel, Arno ;

Werlein, Christopher ;

Stark, Helge ;

Tzankov, Alexandar ;

Li, William W. ;

Li, Vincent W. ;

Mentzer, Steven J. ;

Jonigk, Danny .

NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (02) :120-128

[2]

Adapa Sreedhar, 2020, J Clin Med Res, V12, P276, DOI 10.14740/jocmr4160

[3] Clinical Decision Support for In-Hospital AKI [J].

Al-Jaghbeer, Mohammed ;

Dealmeida, Dilhari ;

Bilderback, Andrew ;

Ambrosino, Richard ;

Kellum, John A. .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2018, 29 (02) :654-660

[4] Peritoneal dialysis in the time of coronavirus disease 2019 [J].

Alfano, Gaetano ;

Fontana, Francesco ;

Ferrari, Annachiara ;

Guaraldi, Giovanni ;

Mussini, Cristina ;

Magistroni, Riccardo ;

Cappelli, Gianni .

CLINICAL KIDNEY JOURNAL, 2020, 13 (03) :265-268

[5] Extracorporeal techniques for the treatment of critically ill patients with sepsis beyond conventional blood purification therapy: the promises and the pitfalls [J].

Ankawi, Ghada ;

Neri, Mauro ;

Zhang, Jingxiao ;

Breglia, Andrea ;

Ricci, Zaccaria ;

Ronco, Claudio .

CRITICAL CARE, 2018, 22

[6] Buffered solutions versus 0.9% saline for resuscitation in critically ill adults and children [J].

Antequera Martin, Alba M. ;

Barea Mendoza, Jesus A. ;

Muriel, Alfonso ;

Saez, Ignacio ;

Chico-Fernandez, Mario ;

Estrada-Lorenzo, Jose M. ;

Plana, Maria N. .

COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2019, (07)

[7] Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State [J].

Arentz, Matt ;

Yim, Eric ;

Klaff, Lindy ;

Lokhandwala, Sharukh ;

Riedo, Francis X. ;

Chong, Maria ;

Lee, Melissa .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (16) :1612-1614

[8]

Argenziano Michael G, 2020, medRxiv, DOI 10.1101/2020.04.20.20072116

[9] Nutrition in critically ill patients with COVID-19: Challenges and special considerations [J].

Arkin, Nicole ;

Krishnan, Kumar ;

Chang, Marvin G. ;

Bittner, Edward A. .

CLINICAL NUTRITION, 2020, 39 (07) :2327-2328

[10] Organ crosstalk: the potent roles of inflammation and fibrotic changes in the course of organ interactions [J].

Armutcu, Ferah .

INFLAMMATION RESEARCH, 2019, 68 (10) :825-839

← 1 2 3 4 5 6 7 8 9 10 →