Two New Anti-Tobacco Mosaic Virus Isoindolin-1-Ones from the Leaves of Nicotiana tabacum

被引：0

作者：

Li Xu

Tao Zhou

Jian-Duo Zhang

Le-Le Deng

Jia-Rui Jiang

Wen-Wu Yang

Chun-Bo Liu

Wei-Song Kong

Xue-Mei Li

Guang-Yu Yang

Qiu-Fen Hu

Xin Liu

机构：

[1] Technology Center,Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education

[2] China Tobacco Yunnan Industrial Co.,undefined

[3] Ltd.,undefined

[4] Yunnan Minzu University,undefined

来源：

Chemistry of Natural Compounds | 2021年 / 57卷

关键词：

isoindolin-1-ones; anti-tobacco mosaic virus activity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Two new isoindolin-1-ones, 6-(3-hydroxypropyl)-2,4-dimethylisoindolin-1-one (1) and 4-(hydroxymethyl)-6-(3-hydroxypropyl)-2-methylisoindolin-1-one (2), were isolated from the leaves of Nicotiana tabacum. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compounds 1 and 2 exhibited high anti-TMV activities with inhibition rates of 42.3 and 46.2% at the concentration of 20 μM, respectively.

引用

页码：1047 / 1050

页数：3

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