Synthesis and Antimicrobial Activity of 2-Bromo-7-methyl-5-oxo-5H-1,3,4- thiadiazolo[3,2-a]pyrimidine

被引:0
作者
Salimov T.M. [1 ]
Kukaniev M.A. [2 ]
Sattorov I.T. [1 ]
Osimov D.M. [2 ]
机构
[1] Tajik Veterinary Research Institute, Academy of Agricultural Sciences of Tajikistan, Dushanbe
[2] Nikitin Institute of Chemistry, Academy of Sciences of Tajikistan, Dushanbe
关键词
Organic Chemistry; Antimicrobial Action; Broad Spectrum; Pyrimidine; Antimicrobial Drug;
D O I
10.1007/s11094-005-0141-9
中图分类号
学科分类号
摘要
The synthesis of 2-bromo-7-methyl-5-oxo-5H-1,3,4-thiadiazolo[3,2-a] pyrimidine is described. This compound exhibits a broad spectrum of antimicrobial action and can be useful in the search for new antimicrobial drugs. © 2005 Springer Science+Business Media, Inc.
引用
收藏
页码:311 / 312
页数:1
相关论文
共 50 条
  • [1] Reactions of thioamides and alkali metal salts of dithiocarbamates with 2-bromo-7-methyl-5-oxo-5H-1,3,4-thiazolo[3,2-a]pyrimidine and antimicrobial activity of products
    Kukaniev M.A.
    Salimov T.M.
    Murvatulloeva M.S.
    Imatshoev I.Kh.
    Pharmaceutical Chemistry Journal, 2006, 40 (8) : 421 - 423
  • [2] Synthesis and Crystal Structure of Ethyl 5-(4-Bromophenyl)-7-methyl-3-oxo-2,3-dihidro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate
    Agarkov, Artem
    Nefedova, Anna
    Ovsyannikov, Alexander
    Litvinov, Igor
    Solovieva, Svetlana
    Antipin, Igor
    MOLBANK, 2023, 2023 (01)
  • [3] Crystal Structure of Ethyl (2Z, 5R)-2-benzylidene-7-methyl-3-oxo-5-phenyl-2,3-dihydro-5H-[1,3] Thiazolo [3,2-a] Pyrimidine-6-carboxylate
    Jotani, Mukesh M.
    Baldaniya, Bharat B.
    Jasinski, Jerry P.
    JOURNAL OF CHEMICAL CRYSTALLOGRAPHY, 2009, 39 (12) : 898 - 901
  • [4] Crystal Structure of Ethyl (2Z, 5R)-2-benzylidene-7-methyl-3-oxo-5-phenyl-2,3-dihydro-5H-[1,3] Thiazolo [3,2-a] Pyrimidine-6-carboxylate
    Mukesh M. Jotani
    Bharat B. Baldaniya
    Jerry P. Jasinski
    Journal of Chemical Crystallography, 2009, 39 : 898 - 901
  • [5] Synthesis and Structure of 7-Hydroxy-5-Oxo-2,3-Dihydro-5H-[1,3]Thiazolo[3,2-a]-Pyrimidine-6-Carboxylic Acid Ethyl Ester
    Ukrainets, I. V.
    Grinevich, L. A.
    Alekseeva, T. V.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2017, 51 (01) : 56 - 59
  • [6] Crystal structure of ethyl 5-(3-fluorophenyl)-2-[(4-fluorophenyl) methylidene]7-methyl-3-oxo-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    Krishnamurthy, M. S.
    Nagarajaiah, H.
    Begum, Noor Shahina
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2014, 70 : O1187 - +
  • [7] Crystal structure of ethyl 4-(2,4-dichlorophenyl)-2-methyl-4H-benzo[4,5]-thiazolo[3,2-a]pyrimidine-3-carboxylate
    Sankar, T.
    Naveen, S.
    Lokanath, N. K.
    Gunasekaran, K.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2015, 71 : O306 - U385
  • [8] Regioselective synthesis of new 5-methyl-5H-pyrimido[4′,5′:4,5][1,3]thiazino [3,2-a]perimidines
    Firoozi, Neda
    Bakavoli, Mehdi
    Eshghi, Hossein
    Ramezanian, Navid
    JOURNAL OF SULFUR CHEMISTRY, 2017, 38 (05) : 488 - 495
  • [9] Synthesis and properties of new benzo[4,5]thiazolo[3,2-a]pyrimidine derivatives
    A. A. Harutyunyan
    G. A. Panosyan
    S. G. Chishmarityan
    R. A. Tamazyan
    A. G. Aivazyan
    R. V. Paronikyan
    H. M. Stepanyan
    R. S. Sukasyan
    A. S. Grigoryan
    Russian Journal of Organic Chemistry, 2015, 51 : 711 - 714
  • [10] Synthesis and Biological Evaluation of Polysubstituted 5-Amino-3,7-diphenyl-7H-thiazolo[3,2-a]pyrimidine-6-carbonitriles
    Ren, Xuanxuan
    Yuan, Rui
    Chen, Wen
    Zhou, Hang
    Ye, Fei
    Shi, Xueying
    Hu, Juan
    Zhang, Peng
    Zhou, Shengliang
    Wan, Yu
    Wu, Hui
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 40 (05) : 1266 - 1274