Sensitivity and Specificity of the ADOS-2 Algorithm in a Large German Sample

被引：31
作者：
Medda, Juliane E. [1 ]
Cholemkery, Hannah [1 ]
Freitag, Christine M. [1 ]
机构：
[1] Goethe Univ, Dept Child & Adolescent Psychiat Psychosomat & Ps, Autism Res & Intervent Ctr Excellence, Univ Hosp Frankfurt, Frankfurt, Germany
来源：
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2019年 / 49卷 / 02期
关键词：
Psychometric assessment; Child psychiatric disorder; Autism spectrum disorder; Diagnostic validity; DIAGNOSTIC-OBSERVATION-SCHEDULE; AUTISM SPECTRUM DISORDERS; REVISED ALGORITHM; CHILDREN; RELIABILITY; ADOLESCENTS; VALIDITY; DEFICITS;
D O I：
10.1007/s10803-018-3750-3
中图分类号：
B844 [发展心理学（人类心理学）];
学科分类号：
040202 ;
摘要：
The aim of the present study was to establish diagnostic validity of the new algorithm of the Autism Diagnostic Observation Scale, the ADOS-2, to differentiate between ASD and other clinically relevant psychiatric and developmental disorders in a large German sample. Validity of ADOS and ADOS-2 diagnostic algorithms was established in 826 individuals (n=455 autism, n=216 autism spectrum, n=155 non-ASD patients) by receiver operating curves. Confidence intervals overlapped largely for ADOS and ADOS-2 algorithms, confirming diagnostic validity of both algorithms. Adding information of the Social Communication Questionnaire and the Social Responsiveness Scale resulted in slightly improved classification rates for autism in Module 4. We thus replicated previous findings of the diagnostic validity of the ADOS-2 algorithms.
引用
收藏
页码：750 / 761
页数：12
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