Histone deacetylase inhibition activates Nrf2 and protects against osteoarthritis

被引:0
|
作者
Dawei Cai
Shasha Yin
Jun Yang
Qing Jiang
Wangsen Cao
机构
[1] Nanjing University School of Medicine,Jiangsu Key Laboratory of Molecular Medicine
[2] Nanjing Drum Tower Hospital Affiliated with Nanjing University School of Medicine,Center of Diagnosis and Treatment for Joint Disease
[3] Model Animal Research Center of Nanjing University,National Clinical Research Center of Kidney Diseases, Jinling Hospital
[4] Nanjing University School of Medicine,undefined
关键词
Cartilage Damage; Nrf2 Signaling; Nrf2 Signaling Pathway; Nrf2 Nuclear Translocation; Meniscotibial Ligament;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] Nrf2 epigenetic derepression induced by running exercise protects against osteoporosis
    Xingren Chen
    Xiaobo Zhu
    Ai Wei
    Fang Chen
    Qi Gao
    Ke Lu
    Qing Jiang
    Wangsen Cao
    Bone Research, 9
  • [42] Nrf2 Protects Against TWEAK-mediated Skeletal Muscle Wasting
    Othman Al-Sawaf
    Athanassios Fragoulis
    Christian Rosen
    Yuet Wai Kan
    Tolga Taha Sönmez
    Thomas Pufe
    Christoph Jan Wruck
    Scientific Reports, 4
  • [43] Histone deacetylase inhibition protects hearing against acute ototoxicity by activating the Nf-κB pathway
    W S Layman
    D M Williams
    J A Dearman
    M A Sauceda
    J Zuo
    Cell Death Discovery, 1
  • [44] Histone deacetylase inhibition protects hearing against acute ototoxicity by activating the Nf-κB pathway
    Layman, W. S.
    Williams, D. M.
    Dearman, J. A.
    Sauceda, M. A.
    Zuo, J.
    CELL DEATH DISCOVERY, 2015, 1
  • [45] Sappanone A Protects Against Myocardial Ischemia Reperfusion Injury by Modulation of Nrf2
    Shi, Xiaojing
    Tao, Guizhou
    Ji, Lili
    Tian, Ge
    DRUG DESIGN DEVELOPMENT AND THERAPY, 2020, 14 : 61 - 70
  • [46] Nrf2 protects against As(III)-induced damage in mouse liver and bladder
    Jiang, Tao
    Huang, Zheping
    Chan, Jefferson Y.
    Zhang, Donna D.
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2009, 240 (01) : 8 - 14
  • [47] Natural compounds protect against the pathogenesis of osteoarthritis by mediating the NRF2/ARE signaling
    Wu, Zhenyu
    Yang, Zhouxin
    Liu, Luying
    Xiao, Yong
    FRONTIERS IN PHARMACOLOGY, 2023, 14
  • [48] Nrf2 protects the lung against inflammation induced by titanium dioxide nanoparticles: A positive regulator role of Nrf2 on cytokine release
    Delgado-Buenrostro, Norma L.
    Medina-Reyes, Estefany I.
    Lastres-Becker, Isabel
    Freyre-Fonseca, Veronica
    Ji, Zhaoxia
    Hernandez-Pando, Rogelio
    Marquina, Brenda
    Pedraza-Chaverri, Jose
    Espada, Sandra
    Cuadrado, Antonio
    Chirino, Yolanda I.
    ENVIRONMENTAL TOXICOLOGY, 2015, 30 (07) : 782 - 792
  • [49] Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload
    Akl, May G.
    Li, Lei
    Baccetto, Raquel
    Phanse, Sadhna
    Zhang, Qingzhou
    Trites, Michael J.
    McDonald, Sherin
    Aoki, Hiroyuki
    Babu, Mohan
    Widenmaier, Scott B.
    CELL REPORTS, 2023, 42 (04):
  • [50] Homoeriodictyol protects human endothelial cells against oxidative insults through activation of Nrf2 and inhibition of mitochondrial dysfunction
    Shen, Tao
    Li, Hai-Zhen
    Li, Ai-Ling
    Li, Yan-Ru
    Wang, Xiao-Ning
    Ren, Dong-Mei
    VASCULAR PHARMACOLOGY, 2018, 109 : 72 - 82