DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer

被引：0
|
作者：
Varun Sasidharan Nair
Salman M. Toor
Rowaida Z. Taha
Hibah Shaath
Eyad Elkord
机构：
[1] Qatar Foundation,Cancer Research Center, Qatar Biomedical Research Institute, College of Science and Engineering, Hamad Bin Khalifa University
[2] Institute of Cancer Sciences,undefined
[3] University of Manchester,undefined
来源：
Clinical Epigenetics | 2018年 / 10卷
关键词：
Colorectal cancer; Immune checkpoints; PD-L1; Galectin-9; DNA methylation; Histone trimethylation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] PD-1、PD-L1、TIM-3表达与食管癌临床病理特征及预后的关系
    杨硕
    陈颖
    实用癌症杂志, 2024, 39 (05) : 778 - 780
  • [42] PD-1/PD-L1、TIM-3表达与食管癌临床病理特征及预后的关系
    刘凯
    刘燕
    黄莉
    刘凯
    重庆医学, 2022, 51 (01) : 65 - 69
  • [43] Foxp3,Galectin-9,PD-L1在小鼠DC2.4细胞的表达
    宫玉波
    黄一飞
    韩根成
    李育蓉
    李新颖
    王大江
    杜改萍
    余继锋
    宋静
    军医进修学院学报, 2011, 32 (01) : 75 - 77
  • [44] Characteristics and clinical correlation of TIM-3 and PD-1/PD-L1 expressions in leukemic cells and tumor microenvironment in newly diagnosed acute myeloid leukemia
    Chajuwan, Thunyamon
    Kansuwan, Patsita
    Kobbuaklee, Sirorat
    Chanswangphuwana, Chantiya
    LEUKEMIA & LYMPHOMA, 2022, 63 (02) : 450 - 456
  • [45] Polymorphisms of co-inhibitory molecules (CTLA-4/PD-1/PD-L1) and the risk of non-small cell lung cancer in a Chinese population
    Ma, Yuan
    Liu, Xiuchun
    Zhu, Jingyan
    Li, Wanhu
    Guo, Liangjun
    Han, Xiao
    Song, Bao
    Cheng, Sensen
    Jie, Liu
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2015, 8 (09): : 16585 - 16591
  • [46] Exosomes-delivered PD-L1 siRNA and CTLA-4 siRNA protect against growth and tumor immune escape in colorectal cancer
    Li, Jian
    Chen, Yuxiang
    Liao, Mingmei
    Yu, Shuyi
    Yuan, Binwen
    Jia, Zeming
    Zhou, Lin
    Tang, Yaping
    GENOMICS, 2023, 115 (04)
  • [47] Immunosuppression of Human Adipose-Derived Stem Cells on T Cell Subsets via the Reduction of NF-kappaB Activation Mediated by PD-L1/PD-1 and Gal-9/TIM-3 Pathways
    Zhou, Kaijian
    Guo, Shu
    Tong, Shuang
    Sun, Qiang
    Li, Fei
    Zhang, Xiaowei
    Qiao, Ying
    Liang, Guoxin
    STEM CELLS AND DEVELOPMENT, 2018, 27 (17) : 1191 - 1202
  • [48] Tumor-Infiltrating T Cells Concurrently Overexpress CD200R with Immune Checkpoints PD-1, CTLA-4, and TIM-3 in Non-Small-Cell Lung Cancer
    Su, Yinghan
    Yamazaki, Shota
    Morisue, Ryo
    Suzuki, Jun
    Yoshikawa, Toshiaki
    Nakatsura, Tetsuya
    Tsuboi, Masahiro
    Ochiai, Atsushi
    Ishii, Genichiro
    PATHOBIOLOGY, 2021, 88 (03) : 218 - 227
  • [49] Triple-Negative Breast Cancer: Intact Mismatch Repair and Partial Co-Expression of PD-L1 and LAG-3
    Wu, Shafei
    Shi, Xiaohua
    Wang, Jing
    Wang, Xuefei
    Liu, Yuanyuan
    Luo, Yufeng
    Mao, Feng
    Zeng, Xuan
    FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [50] Blood Clot Scaffold Loaded with Liposome Vaccine and siRNAs Targeting PD-L1 and TIM-3 for Effective DC Activation and Cancer Immunotherapy
    Chen, Yitong
    Zhang, Yue
    Wang, Beilei
    Fan, Qin
    Yang, Qianyu
    Xu, Jialu
    Dai, Huaxing
    Xu, Fang
    Wang, Chao
    ACS NANO, 2023, 17 (01) : 760 - 774
12345