Brain Morphological Characteristics of Cognitive Subgroups of Schizophrenia-spectrum Disorders and Bipolar Disorder: a Systematic Review with Narrative Synthesis (Feb, 10.1007/s11065-021-09533-0, 2022)

被引:0
|
作者
Karantonis, James A. [1 ,2 ]
Carruthers, Sean P. [1 ,2 ]
Burdick, Katherine E. [6 ,7 ]
Pantelis, Christos [1 ,4 ,5 ]
Green, Melissa [8 ,9 ]
Rossell, Susan L. [2 ,3 ]
Hughes, Matthew E. [2 ]
Cropley, Vanessa [1 ,2 ]
Van Rheenen, Tamsyn E. [1 ,2 ]
机构
[1] Melbourne Neuropsychiat Ctr, Level 3,Alan Gilbert Bldg,161 Barry St, Carlton, Vic 3053, Australia
[2] Swinburne Univ, Ctr Mental Hlth, Sch Hlth Sci, Fac Hlth Arts & Design, Melbourne, Vic, Australia
[3] St Vincents Hosp, St Vincents Mental Hlth, Fitzroy, Vic, Australia
[4] Florey Inst Neurosci & Mental Hlth, Parkville, Vic, Australia
[5] Univ Melbourne, Dept Elect & Elect Engn, Melbourne, Vic, Australia
[6] Brigham & Womens Hosp, 75 Francis St, Boston, MA 02115 USA
[7] Harvard Med Sch, Dept Psychiat, Boston, MA 02115 USA
[8] Univ New South Wales UNSW, Sch Psychiat, Sydney, NSW, Australia
[9] Neurosci Res Australia, Randwick, NSW, Australia
基金
英国医学研究理事会; 澳大利亚国家健康与医学研究理事会;
关键词
Bipolar disorder; Cognition; Cognitive subgroups; Heterogeneity; Morphology; Schizophrenia;
D O I
10.1007/s11065-022-09541-8
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Despite a growing body of research, there is yet to be a cohesive synthesis of studies examining differences in brain morphology according to patterns of cognitive function among both schizophrenia-spectrum disorder (SSD) and bipolar disorder (BD) individuals. We aimed to provide a systematic overview of the morphological differences—inclusive of grey and white matter volume, cortical thickness, and cortical surface area—between cognitive subgroups of these disorders and healthy controls, and between cognitive subgroups themselves. An initial search of PubMed and Scopus databases resulted in 1486 articles of which 20 met inclusion criteria and were reviewed in detail. The findings of this review do not provide strong evidence that cognitive subgroups of SSD or BD map to unique patterns of brain morphology. There is preliminary evidence to suggest that reductions in cortical thickness may be more strongly associated with cognitive impairment, whilst volumetric deficits may be largely tied to the presence of disease. © 2022, The Author(s).
引用
收藏
页码:221 / 221
页数:1
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