4-Aryl(indol-3-yl)-2-pyrrolidone-3(5)-carboxamides: synthesis and structure

被引：1

作者：

Gorodnicheva, N. V. ^{[1
]}

Vasil'eva, O. S. ^{[1
]}

Ostroglyadov, E. S. ^{[1
]}

Baichurin, R. I. ^{[1
]}

Litvinov, I. A. ^{[2
]}

Makarenko, S. V. ^{[1
]}

机构：

[1] Herzen State Pedag Univ Russia, 48 Nab R Moiki, St Petersburg 191186, Russia

[2] Russian Acad Sci, Fed Res Ctr Kazan Sci Ctr, AE Arbuzov Inst Organ & Phys Chem, 8 Ul Akademika Arbuzova, Kazan 420088, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2024年 / 73卷 / 03期

关键词：

racetams; 2-pyrrolidone; 2-pyrrolidone carboxamides; molecular structure; X-ray diffraction analysis; STEREOSELECTIVE-SYNTHESIS; DERIVATIVES;

D O I：

10.1007/s11172-024-4172-3

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of methyl 4-aryl(indol-3-yl)-2-pyrrolidone-3(5)-carboxylates with ammonia afforded racemic (3R*,4S*)-4-(indol-3-yl)-2-pyrrolidone-3-carboxamides and (4R*,5R*)-4-aryl-2-pyrrolidone-5-carboxamides. The three-dimensional structures of these compounds were determined by X-ray diffraction analysis.

引用

页码：624 / 633

页数：10

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