Mx Scripts Library: Structural Equation Modeling Scripts for Twin and Family Data

被引：0
作者：
D Posthuma
D. I. Boomsma
机构：
[1] Vrije Universiteit,Department of Biological Psychology
来源：
Behavior Genetics | 2005年 / 35卷
关键词：
Genetic analysis; Mx; structural equation modeling; twin and family data;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Structural equation modeling (SEM) provides a flexible tool to carry out genetic analyses of family and twin data. The basic model which decomposes the variance between and within families for a particular trait into genetic and non-genetic components can be generalized to multivariate and/ or longitudinal data, incorporate sex differences in parameter estimates, and model the effects of measured environment, candidate genes or DNA marker data. We introduce a web-based library (http://www.psy.vu.nl/mxbib) of scripts for uni- and multivariate genetic epidemiological analyses, as well as for linkage and genetic association tests. The scripts are written to be used with the freely available software package Mx and provide a flexible and uniform approach to the analysis of data from relatives.
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页码：499 / 505
页数：6
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