Effective synthesis of 7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines

被引：0

作者：

Alexander S. Kulikov

Margarita A. Epishina

Leonid L. Fershtat

Nina N. Makhova

机构：

[1] Russian Academy of Sciences,N. D. Zelinsky Institute of Organic Chemistry

来源：

Chemistry of Heterocyclic Compounds | 2018年 / 54卷

关键词：

α-bromo ketones; hydrazinylthiadiazines; ortho esters; thiocarbohydrazide; 7; -1,2,4-triazolo[3,4-; ][1,3,4]thiadiazines; condensation;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

A highly effective method for the preparation of 7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines was developed on the basis of condensation reaction between aryl(hetaryl) α-bromo ketones and commercially available thiocarbohydrazide, followed by treatment of the obtained 2-hydrazinyl-6H-1,3,4-thiadiazine hydrobromides with ortho esters in the presence of trifluoroacetic acid under mild conditions.

引用

页码：669 / 672

页数：3

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