Physicochemical Properties and Methods of Analysis of Vildagliptin (Review)

被引:0
作者
E. B. Polyakova
D. R. Sabirzyanov
N. A. Prozorova
A. V. Foteeva
机构
[1] OOO Parma Clinical,Perm State Pharmaceutical Academy
[2] Russian Ministry of Health,undefined
来源
Pharmaceutical Chemistry Journal | 2022年 / 56卷
关键词
vildagliptin; dipeptidylpeptidase-4 inhibitors; physicochemical properties; analysis methods;
D O I
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中图分类号
学科分类号
摘要
Vildagliptin is an oral agent which is a member of a new class of hypoglycemic drugs, dipeptidylpeptidase-4 (DPP-4) inhibitors. This review presents the physicochemical properties of vildagliptin and assesses analysis methods for its estimation in substances, medicinal formulations, and biological media. These are chromatographic, spectrophotometric, electrochemical and other analysis methods. The material presented may be useful for developing new methods for analysis of medicinal formulations containing vildagliptin. The most widely used method for assay of vildagliptin is HPLC.
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页码:110 / 117
页数:7
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