Factors Associated with Dose Determination of Radioactive Iodine Therapy for Differentiated Thyroid Cancer

被引:13
作者
Hong C.M. [1 ,2 ]
Ahn B.-C. [1 ,2 ]
机构
[1] Department of Nuclear Medicine, School of Medicine, Kyungpook National University, 680, Gukchaebosang-ro, Jung-gu, Daegu
[2] Department of Nuclear Medicine, Kyungpook National University Hospital, 130 Dongdeok-ro, Jung-gu, Daegu
基金
新加坡国家研究基金会;
关键词
Differentiated thyroid cancer; High dose; I-131; Low dose; Radioactive iodine;
D O I
10.1007/s13139-018-0522-0
中图分类号
学科分类号
摘要
Radioactive iodine (RAI) therapy for differentiated thyroid cancer has been successfully used for more than 70 years. However, there is still plenty of controversy surrounding the use and doses of radioiodine. There is insufficient evidence to answer the questions. Recent American Thyroid Association (ATA) guidelines seem to favor low-dose RAI, based on recent clinical trials and meta-analyses. However, long-term follow-up data remains limited, and there are additional factors we should consider that might affect the efficacy of RAI therapy. Therefore, until sufficient data are available, it is necessary to remain cautious about determining RAI doses by considering multiple patient-specific variables. © 2018, Korean Society of Nuclear Medicine.
引用
收藏
页码:247 / 253
页数:6
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