Randomized trial of telephone versus in-person delivery of a brief psychosocial intervention in post-stroke depression NCT01133106 NCT

被引：14

作者：

Kirkness C.J. ^{[1
]}

Cain K.C. ^{[2
]}

Becker K.J. ^{[3
]}

Tirschwell D.L. ^{[3
]}

Buzaitis A.M. ^{[4
]}

Weisman P.L. ^{[1
]}

McKenzie S. ^{[5
]}

Teri L. ^{[6
]}

Kohen R. ^{[7
]}

Veith R.C. ^{[7
]}

Mitchell P.H. ^{[1
,8
]}

机构：

[1] Biobehavioral Nursing and Health Informatics, University of Washington, Box 357266, Seattle, 98195-7266, WA

[2] Biostatistics and School of Nursing, University of Washington, Box 357232, Seattle, 98195-7232, WA

[3] Neurology, University of Washington, Box 359775, Seattle, 98185-9775, WA

[4] UW Medicine, University of Washington, Box 359556, Seattle, 98195-9556, WA

[5] University of Washington, School of Nursing, Box 357266, Seattle, 98195-7266, WA

[6] Psychosocial and Community Health, University of Washington, Box 357263, Seattle, 98195-7263, WA

[7] Psychiatry and Behavioural Sciences, University of Washington, Box 356560, Seattle, 98195-356560, WA

[8] Biobehavioral Nursing and Health Systems, University of Washington, Box 357260, Seattle, 98195-7260, WA

来源：

BMC Research Notes | / 10卷 / 1期

基金：

美国国家卫生研究院;

关键词：

Behavioural therapy; Depression; Nurse therapist; Psychosocial intervention; Randomized controlled trial; Stroke;

D O I：

10.1186/s13104-017-2819-y

中图分类号：

学科分类号：

摘要：

Background: A psychosocial behavioral intervention delivered in-person by advanced practice nurses has been shown effective in substantially reducing post-stroke depression (PSD). This follow-up trial compared the effectiveness of a shortened intervention delivered by either telephone or in-person to usual care. To our knowledge, this is the first of current behavioral therapy trials to expand the protocol in a new clinical sample. 100 people with Geriatric Depression Scores ≥ 11 were randomized within 4 months of stroke to usual care (N = 28), telephone intervention (N = 37), or in-person intervention (N = 35). Primary outcome was response [percent reduction in the Hamilton Depression Rating Scale (HDRS)] and remission (HDRS score < 10) at 8 weeks and 12 months post treatment. Results: Intervention groups were combined for the primary analysis (pre-planned). The mean response in HDRS scores was 39% reduction for the combined intervention group (40% in-person; 38% telephone groups) versus 33% for the usual care group at 8 weeks (p = 0.3). Remission occurred in 37% in the combined intervention groups at 8 weeks versus 27% in the control group (p = 0.3) and 44% intervention versus 36% control at 12 months (p = 0.5). While favouring the intervention, these differences were not statistically significant. Conclusions: A brief psychosocial intervention for PSD delivered by telephone or in-person did not reduce depression significantly more than usual care. However, the comparable effectiveness of telephone and in-person follow-up for treatment of depression found is important given greater accessibility by telephone and mandated post-hospital follow-up for comprehensive stroke centers. © 2017 The Author(s).

引用

共 26 条

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