Porous hydroxyapatite scaffolds containing calcium phosphate glass-ceramics processed using a freeze/gel-casting technique

被引:0
作者
Tae Wan Kim
Su Chak Ryu
Byung Kyu Kim
Seog Young Yoon
Hong Chae Park
机构
[1] Pusan National University,School of Materials Science and Engineering
[2] Pusan National University,Department of Nanomedical Engineering
[3] Pusan National University,Department of Polymer Science and Engineering
来源
Metals and Materials International | 2014年 / 20卷
关键词
biomaterials; ceramics; sintering; strength; scanning electron microscopy (SEM);
D O I
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中图分类号
学科分类号
摘要
A freeze/gel-casting technique has been applied to produce porous ceramic composite scaffolds with tailored pore structures and improved compressive strength for tissue engineering applications. Tertiary-butyl alcohol (TBA)-based hydroxyapatite/calcium phosphate glass-ceramic suspensions with 5–15 vol.% solid loading were used in this study. Following sintering at 1050–1250 °C, the composite scaffolds were characterized in terms of microstructure, and physical and mechanical properties. The resulting scaffolds consisted of unidirectional pore channels (macro-sized) aligned in the solidification direction of the TBA solvent used in the freeze casting step and a few inter/intra-granular pores with small diameter (micron sized) remained in the wall structures of the pore channels by gel casting. With the addition of glass-ceramics (≤10 wt%), a liquid phase was formed mainly by the melting of calcium phosphate glasses at a given sintering temperature. The wall structures became more densified (less porous) aided by liquid phase sintering, possibly lending enhanced compressive strength.
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页码:135 / 140
页数:5
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