The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein

被引：0

作者：

Joel D Pearson

Zubair Mohammed

Julinor T C Bacani

Raymond Lai

Robert J Ingham

机构：

[1] University of Alberta,Department of Medical Microbiology and Immunology

[2] University of Alberta,Department of Laboratory Medicine and Pathology

来源：

BMC Cancer | / 12卷

关键词：

Anaplastic Large Cell Lymphoma; Crizotinib; Hsp90 Inhibitor; Client Protein; Luciferase Reporter Construct;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 482 条

[1]

Amin HM(2007)Pathobiology of ALK+ anaplastic large-cell lymphoma Blood 110 2259-2267

[2]

Lai R(2008)The anaplastic lymphoma kinase in the pathogenesis of cancer Nat Rev Cancer 8 11-23

[3]

Chiarle R(2008)A mouse model for EML4-ALK-positive lung cancer Proc Natl Acad Sci U S A 105 19893-19897

[4]

Voena C(2008)Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer Cancer Res 68 4971-4976

[5]

Ambrogio C(2008)EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer Clin Cancer Res 14 4275-4283

[6]

Piva R(2010)Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer N Engl J Med 363 1693-1703

[7]

Inghirami G(2000)TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors Am J Pathol 157 377-384

[8]

Soda M(1999)Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors Cancer Res 59 2776-2780

[9]

Takada S(2010)Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor N Engl J Med 363 1727-1733

[10]

Takeuchi K(1994)Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin’s lymphoma Science 263 1281-1284